α-Pyrrolidinopentiophenone (α-PVP)

α-PVP

Salts []
Hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	231.33 g/mol ^[1]
Predicted LogP	3.4 ^[1]

Structural Identifiers []
Molecular formula	C₁₅H₂₁NO ^[1]
IUPAC name	1-phenyl-2-pyrrolidin-1-ylpentan-1-one ^[1]
SMILES	CCCC(C(=O)C1=CC=CC=C1)N2CCCC2 ^[1]
InChI	InChI=1S/C15H21NO/c1-2-8-14(16-11-6-7-12-16)15(17)13-9-4-3-5-10-13/h3-5,9-10,14H,2,6-8,11-12H2,1H3 ^[1]
InChIKey	YDIIDRWHPFMLGR-UHFFFAOYSA-N ^[1]

Dosing []
Elimination half-life	2 hours
Duration of action	3 – 5 hours

α-Pyrrolidinopentiophenone

α-Pyrrolidinopentiophenone (also known as α-pyrrolidinovalerophenone, Desmethyl pyrovalerone, O-2387, J3.169.878b, α-PVP, Flakka, Prolintanone, β-Ketone-prolintane, β-Keto-prolintane or Gravel) is a stimulant substance of the pyrrolidinophenone class.

Chemistry

Salts []

α-Pyrrolidinopentiophenone is typically found in the form of its hydrochloride salt.

Stereochemistry []

α-Pyrrolidinopentiophenone is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-α-Pyrrolidinopentiophenone (-)-α-Pyrrolidinopentiophenone

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Australia: α-Pyrrolidinopentiophenone is a S8 substance.
Brazil: α-Pyrrolidinopentiophenone is a F2 substance.^[3]
Canada: α-Pyrrolidinopentiophenone is a Unscheduled substance.
United Kingdom: α-Pyrrolidinopentiophenone is a Class B substance.
United States: α-Pyrrolidinopentiophenone is a Schedule I under the "Controlled Substances Act (CSA)".
Germany: α-Pyrrolidinopentiophenone is a Anlage II substance.
New Zealand: α-Pyrrolidinopentiophenone is a Unscheduled substance.
United Nations: α-Pyrrolidinopentiophenone is a Schedule II drug under the "Convention on Psychotropic Substances 1971".

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 11148955, α-Pyrrolidinopentiophenone. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/11148955
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. α-Pyrrolidinopentiophenone. UNII: 767K3AWA4R. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/767K3AWA4R
Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed July 13, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

Anodyne