α-PiHP

Salts []
α-Pyrrolidinoisohexanophenone hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	245.36 g/mol ^[1]
Predicted LogP	3.9 ^[1]

Structural Identifiers []
Molecular formula	C₁₆H₂₃NO ^[1]
IUPAC name	4-methyl-1-phenyl-2-pyrrolidin-1-ylpentan-1-one ^[1]
SMILES	CC(C)CC(C(=O)C1=CC=CC=C1)N2CCCC2 ^[1]
InChI	InChI=1S/C16H23NO/c1-13(2)12-15(17-10-6-7-11-17)16(18)14-8-4-3-5-9-14/h3-5,8-9,13,15H,6-7,10-12H2,1-2H3 ^[1]
InChIKey	UOZWZANRCOALQL-UHFFFAOYSA-N ^[1]

α-Pyrrolidinoisohexanophenone

α-Pyrrolidinoisohexanophenone (also known as α-Pihp, 4'-Me-pvp, 4-Methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one, α-Pyrrolidinoisohexaphenone, α-PHIP, α-PIHP, 948-236-1, 1-Pentanone, 4-methyl-1-phenyl-2-(1-pyrrolidinyl)-, 4-methyl-α-pyrrolidinopentanophenone or C22829) is a stimulant substance of the pyrrolidinophenone class.

Chemistry

Salts []

α-Pyrrolidinoisohexanophenone is typically found in the form of its hydrochloride salt.

Stereochemistry []

α-Pyrrolidinoisohexanophenone is a racemic mixture of the enantiomers

Stereoisomers
(R)-α-Pyrrolidinoisohexanophenone (S)-α-Pyrrolidinoisohexanophenone

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 59809191, α-Pyrrolidinoisohexanophenone. Accessed August 19, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/59809191
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. α-Pyrrolidinoisohexanophenone. UNII: 9AF2IHV9HK. Global Substance Registration System. Accessed August 19, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/9AF2IHV9HK

Anodyne