Anodyne

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Tapentadol
Tapentadol
Salts
[]
Tapentadol tartrate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Tapentadol maleate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Tapentadol phosphate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Tapentadol hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Tapentadol hydrobromide
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Rotamer
[]
Conformer structure via 3Dmol.js
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Physical properties
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221.34 g/mol [1]
Melting point202-205 [1]
3.5 [1]
Structural Identifiers
[]
C14H23NO [1]
3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol [1]
CC[C@@H](C1=CC(=CC=C1)O)[C@@H](C)CN(C)C [1]
InChI=1S/C14H23NO/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12/h6-9,11,14,16H,5,10H2,1-4H3/t11-,14+/m0/s1 [1]
InChIKeyKWTWDQCKEHXFFR-SMDDNHRTSA-N [1]
Pharmacokinetics[]
Elimination half-life4 hours
Duration of action4 – 6 hours

Tapentadol

Tapentadol (also known as Tapentadol, 175591-23-8, CG5503, Bn 200, Cg5503, BN 200, BN-200, CG-5503, CG5503 IR or 3-((1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl)phenol) is a substance of the phenylpropylamine class.

Chemistry

Salts []

Tapentadol is typically found in the form of its tartrate, maleate, phosphate, hydrochloride and hydrobromide salts.

 []

Tapentadol is a absolute mixture

Legal status []

  • Australia: Tapentadol is a S8 substance.
  • Brazil: Tapentadol is a A1 substance.[3]
  • Canada: Tapentadol is a Schedule I substance.
  • Germany: Tapentadol is a Anlage III substance.
  • United Kingdom: Tapentadol is a Class A (Schedule 2 CD) substance.
  • United States: Tapentadol is a List of Schedule II drugs (US)|Schedule II substance.[4]
  • European Union: Tapentadol is a prescription only substance.
  • United Nations: Tapentadol is a Unscheduled substance.

See also []

  • Substituted phenylpropylamines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 9838022, Tapentadol. Accessed January 2, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/9838022

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Tapentadol. UNII: H8A007M585. Global Substance Registration System. Accessed January 2, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/H8A007M585

    3. Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed January 2, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992

    4. Tapentadol. MedLine Plus. March 15, 2024. Accessed January 2, 2026. https://medlineplus.gov/druginfo/meds/a610006.html