Anodyne| Scopolamine | |
|---|---|
| Salts [] | |
|---|---|
| Scopolamine hemisulfate | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 303.35 g/mol [1] |
| Appearance | Viscous liquid [1] |
| Melting point | 387 ° [1] |
| Solubility | greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) [1] |
| Predicted LogP | 0.9 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C17H21NO4 [1] |
| IUPAC name | [(1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate [1] |
| SMILES | CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4 [1] |
| InChI | InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11?,12-,13-,14+,15-,16+/m1/s1 [1] |
| InChIKey | STECJAGHUSJQJN-USLFZFAMSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 5 hours |
| Toxicity [] | |
|---|---|
| TDLo | Human: - subcutaneous: 2 μg/kg - intramuscular: 4 μg/kg Human - male: - subcutaneous: 14 μg/kg - intramuscular: 24 μg/kg Human - female: - subcutaneous: 13 μg/kg |
| LDLo | Rabbit: - subcutaneous: 75 mg/kg - intravenous: 50 mg/kg |
| LD50 | Rat: - oral: 2650 mg/kg Mouse: - oral: 1275 mg/kg - intraperitoneal: 400 mg/kg - subcutaneous: 1700 mg/kg - intravenous: 100 mg/kg |
Scopolamine
Scopolamine (also known as Scopace, Boro-Scopol, RefChem:570028, Hyoscine, 51-34-3, Scopine (-)-tropate, Scopine tropate, 6,7-Epoxytropine tropate, Atrochin or Atroquin) is a
Chemistry
Salts []
Scopolamine is typically found in the form of its hemisulfate salt.
Stereochemistry []
Scopolamine is a absolute mixture
Legal status
- Australia: Scopolamine is a S4 substance.[3]
- United Kingdom: Scopolamine is a prescription only substance.
- United States: Scopolamine is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3000322, Scopolamine. Accessed September 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/3000322
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Scopolamine. UNII: DL48G20X8X. Global Substance Registration System. Accessed September 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/DL48G20X8X
Poisons Standard October 2020. September 30, 2020. Accessed September 14, 2025. https://www.legislation.gov.au/Details/F2020L01255