| Rosuvastatin | |
|---|---|
| Salts [] | |
|---|---|
| Sodium Rosuvastatin | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 481.5 g/mol [1] |
| Solubility | Sparingly soluble in water [1] |
| Predicted LogP | 1.6 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C22H28FN3O6S [1] |
| IUPAC name | (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid [1] |
| SMILES | CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C [1] |
| InChI | InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1 [1] |
| InChIKey | BPRHUIZQVSMCRT-VEUZHWNKSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 19 hours |
Rosuvastatin
Rosuvastatin is a
Chemistry
Salts []
Rosuvastatin is typically found in the form of its sodium salt.
Stereochemistry []
Rosuvastatin is a absolute mixture
Legal status
- Australia: Rosuvastatin is a S4 substance.
- Canada: Rosuvastatin is a prescription only substance.[3]
- United Kingdom: Rosuvastatin is a prescription only substance.
- United States: Rosuvastatin is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 446157, Rosuvastatin. Accessed December 17, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/446157
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Rosuvastatin. UNII: 413KH5ZJ73. Global Substance Registration System. Accessed December 17, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/413KH5ZJ73
Crestor Product information. April 25, 2012. Accessed December 17, 2025. https://health-products.canada.ca/dpd-bdpp/info.do?lang=en&code=71404
Anodyne