Papaverine

Papaverine

Salts []
Papaverine hydrochloride
Papaverine sulfate

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	339.4 g/mol [1]
Density	1.337 g/cu cm at 20 °C g/cm3 [1]
Appearance	White prisms from alcohol-diethyl ether; needles from petroleum ether [1]
Melting point	147.5 °C [1]
Boiling point	Sublimes at 135 °C [1]
Decomposition	When heated to decomposition it emits toxic fumes of /oxides of nitrogen/. [1]
Solubility	In water, 3.733X10-5 mg/L at 37.5 °C [1]
Predicted LogP	3.9 [1]

Structural Identifiers []
Molecular formula	C20H21NO4 [1]
IUPAC name	1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline [1]
SMILES	COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC [1]
InChI	InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3 [1]
InChIKey	XQYZDYMELSJDRZ-UHFFFAOYSA-N [1]

Pharmacokinetics[]
Elimination half-life	1.5 – 2 hours

Papaverine (also known as Robaxapap, 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline, 6,7-Dimethoxy-1-veratrylisoquinoline, Pavacap, Papaverinum, Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-, 1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline, NSC-136630, Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxy- or Dtxsid4023418) is a substance of the phenol class.

Chemistry

Pharmacology

ATC Classification

Metabolism