Anodyne

4-HEP
Oxilofrine
Molecular structure via molpic
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Physical properties
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Molecular mass181.23 g/mol [1]
Predicted LogP0.6 [1]
SolubilityPartly miscible [1]
Structural Identifiers
[]
Molecular formulaC10H15NO2 [1]
IUPAC name4-[(1R,2S)-1-hydroxy-2-(methylamino)propyl]phenol [1]
SMILESC[C@@H]([C@@H](C1=CC=C(C=C1)O)O)NC [1]
InChIInChI=1S/C10H15NO2/c1-7(11-2)10(13)8-3-5-9(12)6-4-8/h3-7,10-13H,1-2H3/t7-,10-/m0/s1 [1]
InChIKeyOXFGTKPPFSCSMA-XVKPBYJWSA-N [1]
Dosing

Oxilofrine

Oxilofrine (also known as Methylsynephrin, Methylsympatol, Oxyephedrin, Methyl synephrin, Methyl synephrine, p-Hydroxyephedrine, Oxilofrinum, Oxyephedrine, Oxilofrina or Suprifene) is a sympathomimetic substance of the phenylethanolamine class.

Chemistry

Salts []

Oxilofrine is typically found in the form of its hydrochloride salt.

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 688009, Oxilofrine. Accessed June 26, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/688009

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Oxilofrine. UNII: F49638UBDR. Global Substance Registration System. Accessed June 26, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/F49638UBDR

  3. Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed June 26, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992

  4. Methylsynephrine in Dietary Supplements. February 22, 2023. Accessed June 26, 2025. https://www.fda.gov/food/dietary-supplement-ingredient-directory/methylsynephrine-dietary-supplements