Nefiracetam
| Nefiracetam | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 246.30 g/mol [1] |
| Predicted LogP | 1.4 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C14H18N2O2 [1] |
| IUPAC name | N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide [1] |
| SMILES | CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O [1] |
| InChI | InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17) [1] |
| InChIKey | NGHTXZCKLWZPGK-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 3 – 5 hours[3] |
Nefiracetam (also known as Nefiracetamum, DM-9384, 1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-2-oxo-, NSC-759830, Dtxcid20923, N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide, N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl]acetamide, Translon, DM 9384 or Motiva) is a
Chemistry
Stereochemistry []
Nefiracetam is a achiral mixture.
Druglikeness
Lipinski's rule of five
Nefiracetam matches Lipinski's rule of five.Legal status []
- Australia: Nefiracetam is a S4 substance.
- United States: Nefiracetam is a Unscheduled substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 71157, Nefiracetam. Accessed June 11, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/71157
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Nefiracetam. UNII: 1JK12GX30N. Global Substance Registration System. Accessed June 11, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/1JK12GX30N
Fujimaki Y, Sudo K, Hakusui H, Tachizawa H, Murasaki M. Single- and multiple-dose pharmacokinetics of nefiracetam, a new nootropic agent, in healthy volunteers. The Journal of Pharmacy and Pharmacology. September 1, 1992; 44(9):750–754.