{"Aliases":["Nefiracetamum","DM-9384","1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-2-oxo-","NSC-759830","Dtxcid20923","N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide","N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl]acetamide","Translon","DM 9384","Motiva","Mfcd00209882","DZL-221","2-Oxo-1-pyrrolidineaceto-2',6'-xylidide","Dm9384;dzl-221","Ncgc00186006-01","DMPPA","N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide","Smr001456240","Cas-77191-36-7","CCRIS 6729","Brn 6848330","Nefiracetam, solid","Cas#77191-36-7","Mls004774126","Mls006010195","Schembl135856","Chembl260829","orb1310875","HY-B0340R","DZL 221","Chebi:135004","HMS3261I16","HMS3655N05","HMS3884C18","HMS5080N09","Pharmakon1600-01502315","CDA19136","HY-B0340","Tox21_113521","Tox21_201916","Tox21_303025","Tox21_500447","EBC-03769","NSC759830","Akos015895083","Tox21_113521_1","AB04796","CCG-213818","DB13082","KS-5226","LP00447","NSC 759830","Sdccgsbi-0633714.p001","Ncgc00186006-02","Ncgc00186006-03","Ncgc00186006-04","Ncgc00186006-08","Ncgc00186006-11","Ncgc00256487-01","Ncgc00259465-01","Ncgc00261132-01","AC-15655","AC-32883","SY052956","DB-056185","N0996","NS00068094","SW219212-1","En300-54992","Ab01274721-01","Ab01274721_02","Ab01274721_03","F241232","Sr-01000883754","Sr-01000883754-1","Brd-k65678996-001-04-8","Brd-k65678996-001-05-5","Z79686019","(2-(2-Oxopyrrolidin-1-yl)-n-(2,6-dimethylphenyl)-acetamide)"],"CAS":"77191-36-7","ChemicalClasses":["racetam"],"Chirality":"achiral","DTXSID":"2020923","Druglikeness":{"Lipinski":{"Passes":true,"Violations":0}},"EliminationHalfLife":"3 – 5 hours\u003ca href='#cite_note-3'\u003e\u003csup\u003e[3]\u003c/sup\u003e\u003c/a\u003e","Erowid Experience Reports":[],"Esters":[],"European Community (EC) Number":"636-080-4","Formating":[],"HMDB ID":"HMDB0255503","HeavyAtomCount":18,"IUPACName":"N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide","InChI":"InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17)","InChIKey":"NGHTXZCKLWZPGK-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0164013","Link":"https://id.nlm.nih.gov/mesh/M0164013.html","Name":"nefiracetam","Ref":41},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":43},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":56},{"Id":"M0003803","Link":"https://id.nlm.nih.gov/mesh/M0003803.html","Name":"Central Nervous System Agents","Ref":57},{"Id":"M0018063","Link":"https://id.nlm.nih.gov/mesh/M0018063.html","Name":"Psychotropic Drugs","Ref":58},{"Id":"M0028008","Link":"https://id.nlm.nih.gov/mesh/M0028008.html","Name":"Neuroprotective Agents","Ref":59},{"Id":"M0028009","Link":"https://id.nlm.nih.gov/mesh/M0028009.html","Name":"Nootropic Agents","Ref":60}],"MeSH Pharmacological Classification":[{"Id":"M0003803","Link":"https://id.nlm.nih.gov/mesh/M0003803.html","Name":"Central Nervous System Agent","Ref":57},{"Id":"M0018063","Link":"https://id.nlm.nih.gov/mesh/M0018063.html","Name":"Psychotropic Drug","Ref":58},{"Id":"M0028008","Link":"https://id.nlm.nih.gov/mesh/M0028008.html","Name":"Neuroprotective Agent","Ref":59},{"Id":"M0028009","Link":"https://id.nlm.nih.gov/mesh/M0028009.html","Name":"Nootropic Agent","Ref":60}],"MolecularFormula":"C\u003csub\u003e14\u003c/sub\u003eH\u003csub\u003e18\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"246.30 g/mol","Passes":true,"PubChemId":71157,"PubChemTitle":"Nefiracetam","Records":{"UNII":{"Impurities":[]}},"RefChem":"832135","RefCount":4,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Nefiracetam","Name":"Nefiracetam","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q6039388","Name":"Nefiracetam","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB13082","Name":"Nefiracetam","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/71157","Name":"Nefiracetam","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=77191-36-7","Name":"Nefiracetam","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0255503","Name":"Nefiracetam","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/1JK12GX30N","Name":"Nefiracetam","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID2020923","Name":"Nefiracetam","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 71157, Nefiracetam. Accessed June 11, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/71157\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/71157\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Nefiracetam. UNII: 1JK12GX30N. Global Substance Registration System. Accessed June 11, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/1JK12GX30N\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/1JK12GX30N\u003c/a\u003e","Fujimaki Y, Sudo K, Hakusui H, Tachizawa H, Murasaki M. Single- and multiple-dose pharmacokinetics of nefiracetam, a new nootropic agent, in healthy volunteers. The Journal of Pharmacy and Pharmacology. September 1, 1992; 44(9):750–754."],"SMILES":"CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O","SaltData":[],"Salts":[],"Scheduling":[{"gov":"Australia","ref":[],"schedule":"S4 substance"},{"gov":"United States","ref":[],"schedule":"Unscheduled substance"}],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 96.777 71.379\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".8\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h97v72H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m82.471 46.843-.005-15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m69.267 23.986 13.199 7.617M71.705 22.578l10.76 6.21\"/\u003e\u003c/g\u003e\u003cpath d=\"m69.267 23.986.002-15.249\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m82.471 1.107-13.202 7.63M82.472 3.922l-10.765 6.222\"/\u003e\u003c/g\u003e\u003cpath d=\"m82.471 1.107 13.2 7.617\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m95.668 23.973.003-15.249M93.23 22.566l.002-12.434\"/\u003e\u003c/g\u003e\u003cpath d=\"m82.466 31.603 13.202-7.63M69.269 8.737 56.07 1.119M69.267 23.986l-9.913 5.723M52.79 29.713l-9.92-5.727\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M41.651 24.689V12.938M44.09 24.689V12.938\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M41.651 12.938v5.876M44.09 12.938v5.876\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m42.87 23.986-13.198 7.62M29.672 31.606v11.139M32.854 49.186l9.112 6.702M41.966 55.888l-4.674 14.427M37.292 70.315h-15.24M22.052 70.315l-4.673-14.427M26.49 49.186l-9.111 6.702\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M17.842 57.318 6.335 53.611M18.59 54.997 7.083 51.29\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m6.335 53.611 5.753 1.854M7.083 51.29l5.754 1.854\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M54.176 29.105h.91l2.215 4.185v-4.185h.661v5.001h-.911l-2.221-4.185v4.185h-.654zM54.176 34.677h.678v2.048h2.459v-2.048h.673v5.001h-.673v-2.381h-2.459v2.381h-.678z\"/\u003e\u003c/g\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M42.873 6.701q-.738 0-1.172.553-.429.548-.429 1.495 0 .946.429 1.494.434.547 1.172.547.739 0 1.167-.547.429-.548.429-1.494 0-.947-.429-1.495-.428-.553-1.167-.553m0-.548q1.054 0 1.679.708.631.703.631 1.888 0 1.178-.631 1.887-.625.702-1.679.702-1.053 0-1.684-.702-.631-.703-.631-1.887t.631-1.888q.631-.708 1.684-.708\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M27.779 44.345h.911l2.214 4.185v-4.185h.661v5.001h-.911l-2.22-4.185v4.185h-.655z\" class=\"atom\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M2.876 49.17q-.738 0-1.173.553-.429.548-.429 1.495 0 .946.429 1.494.435.548 1.173.548t1.167-.548q.428-.548.428-1.494 0-.947-.428-1.495-.429-.553-1.167-.553m0-.548q1.053 0 1.679.709.631.702.631 1.887 0 1.178-.631 1.887-.626.702-1.679.702-1.054 0-1.685-.702-.631-.703-.631-1.887t.631-1.887q.631-.709 1.685-.709\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m59.354 29.709 4.956-2.861M59.354 29.709l4.956-2.861M52.79 29.713l-4.96-2.864M52.79 29.713l-4.96-2.864M29.672 42.745v-5.57M32.854 49.186l4.556 3.351M26.49 49.186l-4.556 3.351\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Nefiracetam","UNII":"1JK12GX30N","Violations":0,"Wikidata":"Q6039388","Wikipedia":"Nefiracetam","XLogP":1.4}