Methadone

Molecular structure via molpic based on CDK

Conformer []
Conformer structure via JSmol

Physical properties []
Molecular mass	309.4 g/mol [1]
Melting point	99.5 °C [1]
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/. [1]
Solubility	Platelets from alcohol + ether; mp, 235 °C; bitter taste; UV maximum, 292 nm; solubility (g/100 mL) water, 12; alcohol, 8; isopropanol, 2.4; Practically insoluble in ether, glycerol; pH of a 1% aqueous solution is 4.5-5.6 /Methadone hydrochloride/ [1]
Predicted LogP	3.9 [1]

Structural Identifiers []
Molecular formula	C21H27NO [1]
IUPAC name	6-(dimethylamino)-4,4-diphenylheptan-3-one [1]
SMILES	CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2 [1]
InChI	InChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3 [1]
InChIKey	USSIQXCVUWKGNF-UHFFFAOYSA-N [1]

Oral []
Threshold	0.5 - 1 mg
Light	1 - 5 mg
Common	5 - 10 mg
Strong	10 - 20 mg
Heavy	20 - 29.10000000000001 mg

Statistically derived dosages by Sernyl

Methadone

Methadone (also known as Diaminon, Dolophin, Phenadone, Heptadone, Amidone, Ketalgin, Methadon, Adanon, Physeptone or Algovetin)

Chemistry