Etomethazene

Etomethazene

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	365.5 g/mol ^[1]
Predicted LogP	4.8 ^[1]

Structural Identifiers []
Molecular formula	C₂₃H₃₁N₃O ^[1]
IUPAC name	2-[2-[(4-ethoxyphenyl)methyl]-5-methylbenzimidazol-1-yl]-N,N-diethylethanamine ^[1]
SMILES	CCN(CC)CCN1C2=C(C=C(C=C2)C)N=C1CC3=CC=C(C=C3)OCC ^[1]
InChI	InChI=1S/C23H31N3O/c1-5-25(6-2)14-15-26-22-13-8-18(4)16-21(22)24-23(26)17-19-9-11-20(12-10-19)27-7-3/h8-13,16H,5-7,14-15,17H2,1-4H3 ^[1]
InChIKey	ZARKNPABJGEAOQ-UHFFFAOYSA-N ^[1]

Etomethazene (also known as 5-Methyl Etonitazene, 5-methyl etodesnitazene, 1H-Benzimidazole-1-ethanamine, 2-[(4-ethoxyphenyl)methyl]-N,N-diethyl-5-methyl-, 2-(2-(4-ethoxybenzyl)-5-methyl-1H-benzimidazol-1-yl)-N,N-diethylethan-1-amine, 2-[(4-Ethoxyphenyl)methyl]-N,N-diethyl-5-methyl-1H-benzimidazole-1-ethanamine or 2-[2-[(4-Ethoxyphenyl)methyl]-5-methylbenzimidazol-1-yl]-N,N-diethylethanamine) is a opioid substance of the nitazene class.

Chemistry

Stereochemistry []

Etomethazene is a achiral mixture.

Subjective effects []

class / Opioid

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 168310446, Etomethazene. Accessed June 7, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/168310446
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Etomethazene. UNII: K2MJV9DE7T. Global Substance Registration System. Accessed June 7, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/K2MJV9DE7T

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