Anodyne

E2
Generated by the Chemistry Development Kit (http://github.com/cdk)
Salts
[]
Estradiol hemihydrate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
272.4 g/mol [1]
AppearanceWhite crystalline powder. Prisms from 80% alcohol [1]
OdorOdorless [1]
Melting point178.5 °C [1]
Boiling point445.9±45.0 [1]
DecompositionWhen heated to decomposition it emits acrid smoke and irritating fumes. [1]
SolubilityVery soluble in acetone, ethanol, dioxane [1]
[1]
Structural Identifiers
[]
C18H24O2 [1]
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol [1]
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O [1]
InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 [1]
InChIKeyVOXZDWNPVJITMN-ZBRFXRBCSA-N [1]

Estradiol

Estradiol (also known as Estradiol, estradiol, β-Estradiol, 17β-Estradiol, Oestradiol, Dihydrofolliculin, Estrace, Vivelle, Dihydrotheelin or Dihydroxyestrin)

Chemistry

Salts []

Estradiol is typically found in the form of its hemihydrate salt.

 []

Estradiol is a absolute mixture

Anodyne Usernotes
[]
0xea / Estradiol[hemihydrate] via Transdermallife saving hormone; caused figure changes, breast growth, body hair reduction, skin smoothing and emotional enhancements

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5757, Estradiol. Accessed August 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/5757

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Estradiol. UNII: 4TI98Z838E. Global Substance Registration System. Accessed August 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/4TI98Z838E