Brorphine

Molecular structure via molpic based on CDK

Conformer []

Conformer structure via JSmol

Physical properties []
Molecular mass	400.3 g/mol ^[1]
Predicted LogP	4.6 ^[1]

Structural Identifiers []
Molecular formula	C₂₀H₂₂BrN₃O ^[1]
IUPAC name	3-[1-[1-(4-bromophenyl)ethyl]piperidin-4-yl]-1H-benzimidazol-2-one ^[1]
SMILES	CC(C1=CC=C(C=C1)Br)N2CCC(CC2)N3C4=CC=CC=C4NC3=O ^[1]
InChI	InChI=1S/C20H22BrN3O/c1-14(15-6-8-16(21)9-7-15)23-12-10-17(11-13-23)24-19-5-3-2-4-18(19)22-20(24)25/h2-9,14,17H,10-13H2,1H3,(H,22,25) ^[1]
InChIKey	CNOFBGYRMCBVLO-UHFFFAOYSA-N ^[1]

Brorphine

Brorphine (also known as 3-(1-(1-(4-bromophenyl)ethyl)piperidin-4-yl)-1H-benzimidazol-2-one, 2H-Benzimidazol-2-one, 1-[1-[1-(4-bromophenyl)ethyl]-4-piperidinyl]-1,3-dihydro-, 1-(1-(1-(4-Bromophenyl)ethyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one, 1-(1-(1-(4-Bromophenyl)ethyl)piperidin-4-yl)-1,3-dihydro-2H-benzo(d)imidazol-2-one, 1-[1-[1-(4-Bromophenyl)ethyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, 1-{1-[1-(4-Bromophenyl)ethyl]piperidin-4-yl}-1,3-dihydro-2H-benzo[d]imidazol-2-one, GTPL12956, compound 21, C22777 or 1-(1-(1-(4-Bromophenyl)ethyl)piperidin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one) is a opioid substance of the benzimidazole class.

Chemistry

Stereochemistry []

Brorphine is a racemic mixture of the enantiomers

Stereoisomers
(R)-Brorphine (S)-Brorphine

Subjective effects []

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 145975294, Brorphine. Accessed July 28, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/145975294

Anodyne