Baclofen

Salts []
Baclofen hydrochloride

Molecular structure via molpic
Conformer structure via 3Dmol.js
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Molecular formula	C10H12ClNO2[1]
Molecular mass	213.66 g/mol[1]
Predicted LogP	-1[1]
Melting point	372 to 376 °F (NTP, 1992)[1]
Solubility	less than 1 mg/mL at 64 °F (NTP, 1992)[1]
Chirality	racemic[2]

Identifiers []
IUPAC name	4-amino-3-(4-chlorophenyl)butanoic acid[1]
SMILES	C1=CC(=CC=C1C(CC(=O)O)CN)Cl[1]
InChI	InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)[1]
InChIKey	KPYSYYIEGFHWSV-UHFFFAOYSA-N[1]

Dosing
Elimination half-life	2.5 to 7 hours

Oral []
Threshold	10 mg
Light	10 - 20 mg
Common	20 - 40 mg
Strong	40 - 50 mg
Heavy	50 - 80 mg

Statistically derived dosages by Sernyl

Baclofen

Baclofen (also known as 4-Amino-3-(4-chlorophenyl)butanoic acid, Baclon, Kemstro, DL-Baclofen, Baclofene, Baclofeno, Gabalon, (+-)-Baclofen, Baclofenum or Baclophen) is a substance of the gabapentinoid class.

Chemistry

Baclofen is typically found in the form of its hydrochloride salt.

Stereochemistry

(RS)-Baclofen is a racemic mixture of the optical stereoisomers:

Stereoisomers []
(+)-Baclofen (-)-Baclofen

Legal status

• Australia: Baclofen is a S4 substance.
• Canada: Baclofen is a prescription only substance.
• New Zealand: Baclofen is a Prescription only substance.
• United Kingdom: Baclofen is a prescription only substance.
• United States: Baclofen is a prescription only substance.

See also

• Substituted gabapentinoids
• Anodyne

External links

• Baclofen (Wikipedia)
• Baclofen / (+)-Baclofen / (-)-Baclofen (Wikidata)
• Baclofen / (+)-Baclofen / (-)-Baclofen (DrugBank)
• Baclofen / (+)-Baclofen / (-)-Baclofen (PubChem)
• Baclofen / (+)-Baclofen / (-)-Baclofen (ChEMBL)
• Baclofen / (-)-Baclofen (ChEBI)
• Baclofen / (+)-Baclofen / (-)-Baclofen (Common Chemistry)
• Baclofen (HMDB)
• Baclofen / (-)-Baclofen (KEGG)
• Baclofen / (+)-Baclofen / (-)-Baclofen (UNII)
• Baclofen / (-)-Baclofen (EPA DSSTox)