Acetylfentanyl

Acetylfentanyl

Salts []
Acetylfentanyl hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	322.4 g/mol ^[1]
Predicted LogP	3.6 ^[1]

Structural Identifiers []
Molecular formula	C₂₁H₂₆N₂O ^[1]
IUPAC name	N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]acetamide ^[1]
SMILES	CC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3 ^[1]
InChI	InChI=1S/C21H26N2O/c1-18(24)23(20-10-6-3-7-11-20)21-13-16-22(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3 ^[1]
InChIKey	FYIUUQUPOKIKNI-UHFFFAOYSA-N ^[1]

Acetylfentanyl (also known as Acetyl fentanyl, N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide, Acetamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, Piperidine, 1-phenethyl-4-(N-phenylacetamido)-, N-Phenyl-N-(1-(2-phenylethyl)piperidin-4-yl)acetamide, J125.906G, Acetamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)-, Dtxcid90108766, N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-acetamide or Acetanilide, N-(1-phenethyl-4-piperidyl)-) is a opioid substance of the phenethylpiperidine class.

Chemistry

Salts []

Acetylfentanyl is typically found in the form of its hydrochloride salt.

Stereochemistry []

Acetylfentanyl is a achiral mixture.

Reagents

There are currently 3 reagent-interactions on DrugsPRO

Reagent	Color change
Marquis
Mecke
Mandelin

Subjective effects []

class / Opioid

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

Experience reports []

There are currently 5 experience reports involving acetylfentanyl on Erowid:

Legal status []

Australia: Acetylfentanyl is a Illegal substance.
Brazil: Acetylfentanyl is a F1 substance.
Canada: Acetylfentanyl is a Schedule I substance.^[3]
Germany: Acetylfentanyl is a Anlage II substance.
United Kingdom: Acetylfentanyl is a Class A substance.
United States: Acetylfentanyl is a Schedule I under the "Controlled Substances Act (CSA)".

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 527015, Acetylfentanyl. Accessed May 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/527015
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Acetylfentanyl. UNII: 6DZ28538KS. Global Substance Registration System. Accessed May 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/6DZ28538KS
Controlled Drugs and Substances Act. Accessed May 24, 2026. https://isomerdesign.com/Cdsa/schedule.php?schedule=1§ion=16&structure=C

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