Threonine
| Thr | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 119.12 g/mol [1] |
| Appearance | Colorless crystals [1] |
| Melting point | 256 °C [1] |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitric oxide/. [1] |
| Solubility | Insoluble in ethanol, ethyl ether, chloroform [1] |
| Predicted LogP | -2.9 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C4H9NO3 [1] |
| IUPAC name | (2S,3R)-2-amino-3-hydroxybutanoic acid [1] |
| SMILES | C[C@H]([C@@H](C(=O)O)N)O [1] |
| InChI | InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1 [1] |
| InChIKey | AYFVYJQAPQTCCC-GBXIJSLDSA-N [1] |
Threonine (also known as 72-19-5, 2-amino-3-hydroxybutanoic acid, Threonin, 2-amino-3-hydroxybutyric acid, Treonina, 2-Amino-3-hydroxybutyric acid, Threoninum, thr, (2S)-threonine or α-Amino-β-hydroxybutyric acid) is a
Chemistry
Stereochemistry []
Threonine is a achiral mixture of the logical stereoisomers.
Druglikeness
Lipinski's rule of five
Threonine matches Lipinski's rule of five.See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 6288, Threonine. Accessed June 13, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/6288
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Threonine. UNII: TFM6DU5S6A. Global Substance Registration System. Accessed June 13, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/TFM6DU5S6A