Thiothinone

Salts []
Hydrochloride

Molecular structure via molpic based on CDK

Conformer []

Conformer structure via 3Dmol.js

Physical properties []
Molecular mass	169.25 g/mol ^[1]
Predicted LogP	1.6 ^[1]

Structural Identifiers []
Molecular formula	C₈H₁₁NOS ^[1]
IUPAC name	2-(methylamino)-1-thiophen-2-ylpropan-1-one ^[1]
SMILES	CC(C(=O)C1=CC=CS1)NC ^[1]
InChI	InChI=1S/C8H11NOS/c1-6(9-2)8(10)7-4-3-5-11-7/h3-6,9H,1-2H3 ^[1]
InChIKey	DOZQPYDMJMLVKX-UHFFFAOYSA-N ^[1]

Thiothinone

Thiothinone (also known as 2-Thiothinone, 2-(Methylamino)-1-(2-thienyl)-1-propanone or 1-Propanone, 2-(methylamino)-1-(2-thienyl)-) is a stimulant substance of the thiopropamine class.

Chemistry

Salts []

Thiothinone is typically found in the form of its hydrochloride salt.

Stereochemistry []

Thiothinone is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-Thiothinone (-)-Thiothinone

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Germany: Thiothinone is a Neuer-Psychoaktiver-Stoff under the "Neue-psychoaktive-Stoffe-Gesetz (NpSG)".
United Kingdom: Thiothinone is a Class B substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 12198617, Thiothinone. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/12198617
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Thiothinone. UNII: 8C758Z7L72. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8C758Z7L72

Anodyne