Protonitazene

Protonitazene

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	410.5 g/mol ^[1]
Predicted LogP	4.8 ^[1]

Structural Identifiers []
Molecular formula	C₂₃H₃₀N₄O₃ ^[1]
IUPAC name	N,N-diethyl-2-[5-nitro-2-[(4-propoxyphenyl)methyl]benzimidazol-1-yl]ethanamine ^[1]
SMILES	CCCOC1=CC=C(C=C1)CC2=NC3=C(N2CCN(CC)CC)C=CC(=C3)[N+](=O)[O-] ^[1]
InChI	InChI=1S/C23H30N4O3/c1-4-15-30-20-10-7-18(8-11-20)16-23-24-21-17-19(27(28)29)9-12-22(21)26(23)14-13-25(5-2)6-3/h7-12,17H,4-6,13-16H2,1-3H3 ^[1]
InChIKey	SJHUJFHOXYDSJY-UHFFFAOYSA-N ^[1]

Protonitazene (also known as Dtxcid501771643, Nocas_1342658, Chebi:234363, N,N-Diethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1-yl)ethan-1-amine, Benzimidazole, 1-(2-(diethylamino)ethyl)-5-nitro-2-(p-propoxybenzyl)-, 1H-Benzimidazole-1-ethanamine, N,N-diethyl-5-nitro-2-((4-propoxyphenyl)methyl)-, N,N-Diethyl-5-nitro-2-((4-propoxyphenyl)methyl)-1H-benzimidazole-1-ethanamine, N,N-Diethyl-5-nitro-2-[(4-propoxyphenyl)methyl]-1H-benzimidazole-1-ethanamine, Benzimidazole, 1-[2-(diethylamino)ethyl]-5-nitro-2-(p-propoxybenzyl)- or 1H-Benzimidazole-1-ethanamine, N,N-diethyl-5-nitro-2-[(4-propoxyphenyl)methyl]-) is a opioid substance of the nitazene class.

Chemistry

Stereochemistry []

Protonitazene is a achiral mixture.

Reagents

There are currently 3 reagent-interactions on DrugsPRO

Reagent	Color change
Marquis
Mecke
Mandelin

Subjective effects []

class / Opioid

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 156589001, Protonitazene. Accessed June 7, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/156589001
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Protonitazene. UNII: 4A6RZQ7M2V. Global Substance Registration System. Accessed June 7, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/4A6RZQ7M2V

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