Propylphenidate

PPH

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	261.36 g/mol ^[1]
Predicted LogP	1.1 ^[1]

Structural Identifiers []
Molecular formula	C₁₆H₂₃NO₂ ^[1]
IUPAC name	propyl 2-phenyl-2-piperidin-2-ylacetate ^[1]
SMILES	CCCOC(=O)C(C1CCCCN1)C2=CC=CC=C2 ^[1]
InChI	InChI=1S/C16H23NO2/c1-2-12-19-16(18)15(13-8-4-3-5-9-13)14-10-6-7-11-17-14/h3-5,8-9,14-15,17H,2,6-7,10-12H2,1H3 ^[1]
InChIKey	PRMWWEANNQSWAR-UHFFFAOYSA-N ^[1]

Propylphenidate (also known as Dtxsid101032411, ZDA08850, Propyl α-phenyl-2-piperidineacetate, NS00096970 or Propylphenidate hydrochloride, threo, racemic) is a stimulant substance of the phenidate class.

Chemistry

Stereochemistry []

Propylphenidate is a racemic mixture of the diastereomers.

Stereoisomerism
(6S,7S)-Propylphenidate (6R,7S)-Propylphenidate (6S,7R)-Propylphenidate (6R,7R)-Propylphenidate
Stereoisomer enumberation with rdkit

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Canada: Propylphenidate is a Schedule III substance.
Germany: Propylphenidate is a Neuer-Psychoaktiver-Stoff under the "Neue-psychoaktive-Stoffe-Gesetz (NpSG)".
United Kingdom: Propylphenidate is a Class B substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 91844466, Dtxsid101032411. Accessed May 8, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/91844466

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