Anodyne

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Phenibut
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
179.22 g/mol [1]
-1.6 [1]
Structural Identifiers
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C10H13NO2 [1]
4-amino-3-phenylbutanoic acid [1]
C1=CC=C(C=C1)C(CC(=O)O)CN [1]
InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13) [1]
InChIKeyDAFOCGYVTAOKAJ-UHFFFAOYSA-N [1]
Dosing
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Elimination half-life5.3 hours (250 mg)
Duration of action15 – 24 hours (1 – 3 g)

Phenibut

Phenibut (also known as 4-Amino-3-phenylbutanoic acid, Fenibut, 4-Amino-3-phenylbutyric acid, PhGaba, pheniγ, phenygam, β-Phenyl-γ-aminobutyric acid, β-(Aminomethyl)hydrocinnamic acid, β-(Aminomethyl)benzenepropanoic acid or phenyl-GABA) is a substance of the gabapentinoid class.

Chemistry

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Phenibut is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-PhenibutGenerated by the Chemistry Development Kit (http://github.com/cdk)
(-)-PhenibutGenerated by the Chemistry Development Kit (http://github.com/cdk)

Experience reports []

There are currently 25+ experience reports involving phenibut on OpenErowid:

Legal status []

  • Australia: Phenibut is a S4 substance.
  • Canada: Phenibut is a Unscheduled substance.
  • Germany: Phenibut is a NPSG substance.
  • United States: Phenibut is a Unapproved drug; use in dietary supplements, food, or medicine is unlawful. substance.[3]
  • United Nations: Phenibut is a Unscheduled substance.

See also []

  • Substituted gabapentinoids
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 14113, Phenibut. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/14113

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Phenibut. UNII: T2M58D6LA8. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/T2M58D6LA8

    3. Phenibut in Dietary Supplements. FDA. March 6, 2023;