N-Desethylprotonitazene

N-Desethylprotonitazene

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	382.5 g/mol ^[1]
Predicted LogP	4 ^[1]

Structural Identifiers []
Molecular formula	C₂₁H₂₆N₄O₃ ^[1]
IUPAC name	N-ethyl-2-[5-nitro-2-[(4-propoxyphenyl)methyl]benzimidazol-1-yl]ethanamine ^[1]
SMILES	CCCOC1=CC=C(C=C1)CC2=NC3=C(N2CCNCC)C=CC(=C3)[N+](=O)[O-] ^[1]
InChI	InChI=1S/C21H26N4O3/c1-3-13-28-18-8-5-16(6-9-18)14-21-23-19-15-17(25(26)27)7-10-20(19)24(21)12-11-22-4-2/h5-10,15,22H,3-4,11-14H2,1-2H3 ^[1]
InChIKey	NPHUSRHIDKYNDO-UHFFFAOYSA-N ^[1]

N-Desethylprotonitazene (also known as N-desethyl Protonitazene, 1H-Benzimidazole-1-ethanamine, N-ethyl-5-nitro-2-[(4-propoxyphenyl)methyl]- or N-Ethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1-yl)ethan-1-amine) is a opioid substance of the nitazene class.

Chemistry

Stereochemistry []

N-Desethylprotonitazene is a achiral mixture.

Subjective effects []

class / Opioid

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

Legal status []

Germany: N-Desethylprotonitazene is a Anlage II substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 168310594, N-Desethylprotonitazene. Accessed June 7, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/168310594
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. N-Desethylprotonitazene. UNII: DCT7D53JTM. Global Substance Registration System. Accessed June 7, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/DCT7D53JTM

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