Anodyne

MXE
Methoxetamine
Molecular structure via molpic based on CDK
Physical properties
[]
247.33 g/mol [1]
2.3 [1]
Structural Identifiers
[]
C15H21NO2 [1]
2-(ethylamino)-2-(3-methoxyphenyl)cyclohexan-1-one [1]
CCNC1(CCCCC1=O)C2=CC(=CC=C2)OC [1]
InChI=1S/C15H21NO2/c1-3-16-15(10-5-4-9-14(15)17)12-7-6-8-13(11-12)18-2/h6-8,11,16H,3-5,9-10H2,1-2H3 [1]
InChIKeyLPKTWLVEGBNOOX-UHFFFAOYSA-N [1]
Dosing
[]
Elimination half-life3 – 6 hours

Methoxetamine

Methoxetamine (also known as Mexxy, 3-MeO-2-Oxo-PCE, (RS)2-(3-Methoxyphenyl)-2-(ethylamino)cyclohexanone, 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone, (Rs)-2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone, -2-(3-Methoxyphenyl)-2-(ethylamino)cyclohexanone, juwiqhnnbjaneb-uhfffaoysa-n, cyclohexanone, 2-(ethylamino)-2-(3-methoxyphenyl)-, 2-(ethylaMino)-2-(3-Methoxyphenyl)-1-cyclohexanone or 2-(Ethylamino)-2-(3-methoxyphenyl)cyclohexanone) is a substance of the arylcyclohexylamine class.

Chemistry

Salts []

Methoxetamine is typically found in the form of its hydrochloride salt.

 []

(RS)-Methoxetamine is a racemic mixture of the optical stereoisomers

Experience reports []

Legal status []

  • Brazil: Methoxetamine is a F2 substance.[3]
  • United Kingdom: Methoxetamine is a Class B substance.
  • United States: Methoxetamine is a Controlled Substances Act#Schedule I|Schedule I substance.[4]
  • Germany: Methoxetamine is a Anlage I substance.
  • United Nations: Methoxetamine is a Schedule II drug under the "Convention on Psychotropic Substances 1971".

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 52911279, Methoxetamine. Accessed June 27, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/52911279

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Methoxetamine. UNII: ZO5ZCE6E12. Global Substance Registration System. Accessed June 27, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/ZO5ZCE6E12

  3. Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed June 27, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

  4. Federal Register. FederalRegister.gov. June 6, 2022. Accessed June 27, 2025. https://www.federalregister.gov/documents/2022/06/06/2022-11933/schedules-of-controlled-substances-placement-of-methoxetamine-mxe-in-schedule-i