Anodyne

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Lopirazepam
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Conformer structure via JSmol
Physical properties
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322.1 g/mol [1]
2.7 [1]
Structural Identifiers
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C14H9Cl2N3O2 [1]
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one [1]
C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2N=C(C=C3)Cl)O)Cl [1]
InChI=1S/C14H9Cl2N3O2/c15-8-4-2-1-3-7(8)11-12-9(5-6-10(16)18-12)17-13(20)14(21)19-11/h1-6,14,21H,(H,17,20) [1]
InChIKeyJEJOFYTVMFVKQA-UHFFFAOYSA-N [1]

Lopirazepam

Lopirazepam (also known as 2H-Pyrido(3,2-e)-1,4-diazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-, Lopirazepamum, 3-hydroxy-5-(o-chlorophenyl)-7-chloro-1,2-dihydro-2H-pyrido(3,2-e)-1,4-diazepin-2-one, 255-974-1, Lopirazepam, (+)-, 12524, 52JHG2TV3G, N6X3ET65NY, 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2h-pyrido[3,2-e][1,4]diazepin-2-one or 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-pyrido(3,2,-e)-1,4-diazepin-2-one) is a substance of the pyridodiazepine class.

Chemistry

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Lopirazepam is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-LopirazepamGenerated by the Chemistry Development Kit (http://github.com/cdk)
(-)-LopirazepamGenerated by the Chemistry Development Kit (http://github.com/cdk)

Legal status []

  • United States: Lopirazepam is a Schedule I under the "Controlled Substances Act (CSA)".

See also []

  • Substituted pyridodiazepines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 68672, Lopirazepam. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/68672

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Lopirazepam. UNII: 8PDI6DY6GV. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8PDI6DY6GV