Huperzine A
| HupA | |
|---|---|
 |
| Salts [] | |
|---|---|
| Huperzine A monohydrate | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 242.32 g/mol [1] |
| Melting point | 217-219 °C [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C15H18N2O [1] |
| IUPAC name | (1R,9R,13E)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one [1] |
| SMILES | C/C=C/1\[C@@H]2CC3=C([C@]1(CC(=C2)C)N)C=CC(=O)N3 [1] |
| InChI | InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15+/m0/s1 [1] |
| InChIKey | ZRJBHWIHUMBLCN-YQEJDHNASA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 10 – 14 hours[3] |
(Redirected from Huperzine A)
Huperzine A (also known as huperzine A, huperazine A, Huperzine-A, Hup A, Kimpukan A, Dtxsid8046038, Dtxcid6026038, Chebi:78330, 5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R,9R,11E)- or (5R,9r,11e)-5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta(b)pyridin-2(1h)-one)
Chemistry
Salts []
Huperzine A is typically found in the form of its monohydrate salt.
Stereochemistry []
Huperzine A is a absolute mixture.
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 854026, Huperzine A. Accessed May 11, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/854026
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Huperzine A. UNII: 0111871I23. Global Substance Registration System. Accessed May 11, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/0111871I23
Li YX, Zhang RQ, Li CR, Jiang XH. Pharmacokinetics of huperzine A following oral administration to human volunteers. European Journal of Drug Metabolism and Pharmacokinetics. 2007; 32(4):183–187.