Anodyne

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Homatropine

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Homatropine
Homatropine
Salts
[]
Homatropine hydrobromide
Generated by the Chemistry Development Kit (http://github.com/cdk)
Homatropine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
275.34 g/mol [1]
1.9 [1]
Structural Identifiers
[]
C16H21NO3 [1]
[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate [1]
CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(C3=CC=CC=C3)O [1]
InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3/t12-,13+,14?,15? [1]
InChIKeyZTVIKZXZYLEVOL-DGKWVBSXSA-N [1]

Homatropine (also known as Npc13206, Homatropine, 87-00-3, Homatropin, Homoatropine, Mandelyltropeine, 8QS6WCL55Z, Homotropine, Mandelytropeine or Dtxsid6044014) is a anticholinergic substance of the tropane class.

Chemistry

Salts []

Homatropine is typically found in the form of its hydrobromide and hydrochloride salts.

 []

Homatropine is a racemic mixture of the

(2R,5S)-7r)-12S)-HomatropineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(2R,5S)-7s)-12S)-HomatropineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(2R,5S)-7r)-12R)-HomatropineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(2R,5S)-7s)-12R)-HomatropineGenerated by the Chemistry Development Kit (http://github.com/cdk)
Stereoisomer enumberation with rdkit

Subjective effects []

See also []

  • Substituted tropanes
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5282593, Npc13206. Accessed February 17, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/5282593

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Homatropine. UNII: 8QS6WCL55Z. Global Substance Registration System. Accessed February 17, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8QS6WCL55Z