Anodyne

Diethylpropion

Salts []
Hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	205.30 g/mol ^[1]
Decomposition	When heated to decomp it emits very toxic fumes of /hydrogen chloride and nitrogen oxides./ /Diethylpropion hydrochloride/ ^[1]
Solubility	White or creamy white, small crystals or crystalline powder; characteristic, mildly aromatic odor; 1 g sol in: about 0.6 mL water, about 0.6 ml chloroform, 1 ml absolute methanol, 1 ml alcohol; practically insoluble in ether /Diethylpropion hydrochloride/ ^[1]
Predicted LogP	2.8 ^[1]

Structural Identifiers []
Molecular formula	C₁₃H₁₉NO ^[1]
IUPAC name	2-(diethylamino)-1-phenylpropan-1-one ^[1]
SMILES	CCN(CC)C(C)C(=O)C1=CC=CC=C1 ^[1]
InChI	InChI=1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3 ^[1]
InChIKey	XXEPPPIWZFICOJ-UHFFFAOYSA-N ^[1]

Diethylpropion

Diethylpropion (also known as Amfepramone, Diethylpropione, Amfepramon, Amphepramone, Nopropiophenone, Adiposon, Amphepramon, Frekentine, Danylen or Magrene) is a prodrug and stimulant substance of the cathinone class.

Chemistry

Salts []

Diethylpropion is typically found in the form of its hydrochloride salt.

Stereochemistry []

Diethylpropion is a racemic mixture of the enantiomers

Stereoisomers
(R)-Diethylpropion (S)-Diethylpropion

Pharmacology

Diethylpropion acts as a prodrug for:

Active metabolites []
Ethcathinone

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 7029, Diethylpropion. Accessed July 19, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/7029
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Diethylpropion. UNII: Q94YYU22B8. Global Substance Registration System. Accessed July 19, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/Q94YYU22B8