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Dexmethylphenidate

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d-MPH
Dexmethylphenidate
Salts
[]
Dexmethylphenidate hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
233.31 g/mol [1]
Melting point>203 [1]
0.2 [1]
Structural Identifiers
[]
C14H19NO2 [1]
methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate [1]
COC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2 [1]
InChI=1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3/t12-,13-/m1/s1 [1]
InChIKeyDUGOZIWVEXMGBE-CHWSQXEVSA-N [1]
Pharmacokinetics[]
Elimination half-life4 hours
Dosing[]
Buccal
[]
Light≤ 31.6 mg(12x - 33.3%)
Common31.6 - 40 mg(8x - 22.2%)
Strong40 - 60 mg(10x - 27.8%)
Heavy60 - 85 mg(2x - 5.6%)
Extreme85 mg +(4x - 11.1%)
Insufflated
[]
Light≤ 32.7 mg(76x - 30.4%)
Common32.7 - 40 mg(64x - 25.6%)
Strong40 - 60 mg(49x - 19.6%)
Heavy60 - 116.3 mg(35x - 14%)
Extreme116.3 mg +(26x - 10.4%)
Intravenous
[]
Light≤ 8.8 mg(1x - 25%)
Common8.8 - 10 mg(2x - 50%)
Strong10 - 15 mg
Heavy15 - 24 mg
Extreme24 mg +(1x - 25%)
Subcutaneous
[]
Light≤ 40.9 mg(2x - 66.7%)
Common40.9 mg
Strong40 - 50 mg
Heavy50 - 56 mg
Extreme56 mg +(1x - 33.3%)
Sublingual
[]
Light≤ 34.5 mg(74x - 27.2%)
Common34.5 - 40 mg(80x - 29.4%)
Strong40 - 60 mg(53x - 19.5%)
Heavy60 - 98 mg(37x - 13.6%)
Extreme98 mg +(28x - 10.3%)
Oral
[]
Light≤ 24.8 mg(122x - 43.1%)
Common24.8 - 36 mg(37x - 13.1%)
Strong36 - 72 mg(57x - 20.1%)
Heavy72 - 108 mg(40x - 14.1%)
Extreme108 mg +(27x - 9.5%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Dexmethylphenidate (also known as threo-Methylphenidate, dexmetilfenidato, Attenade, TMP, dexmethylphenidatum, Chebi:51860, methyl (R)-phenyl[(R)-piperidin-2-yl]acetate, Dtxsid70893769, methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate or 2-Piperidineacetic acid, α-phenyl-, methyl ester, (αR,2R)-) is a stimulant substance of the phenidate class.

Chemistry

Salts []

Dexmethylphenidate is typically found in the form of its hydrochloride salt.

 []

Dexmethylphenidate is a absolute mixture.

Pharmacology

In the () dexmethylphenidate acts as a stimulant (), sympathomimetic (), dexmethylphenidate () and psychoanaleptic ().[1]

Metabolism

Subjective effects []

class / Stimulant

Experience reports []

There are currently 25+ experience reports involving dexmethylphenidate on :

 []

  • Australia: Dexmethylphenidate is a Schedule 8 substance.
  • Canada: Dexmethylphenidate is a Schedule III substance.
  • Germany: Dexmethylphenidate is a Anlage III substance.
  • United Kingdom: Dexmethylphenidate is a Class B substance.
  • United States: Dexmethylphenidate is a Schedule I under the "Controlled Substances Act (CSA)".
  • United Nations: Dexmethylphenidate is a Schedule II drug under the "Convention on Psychotropic Substances 1971".

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 154101, Dexmethylphenidate. Accessed May 8, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/154101

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dexmethylphenidate. UNII: M32RH9MFGP. Global Substance Registration System. Accessed May 8, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/M32RH9MFGP