Anodyne| Clotiazepam | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 318.8 g/mol [1] |
| Melting point | 105-106 [1] |
| Solubility | 5.37e-03 g/L [1] |
| Predicted LogP | 3.5 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C16H15ClN2OS [1] |
| IUPAC name | 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one [1] |
| SMILES | CCC1=CC2=C(S1)N(C(=O)CN=C2C3=CC=CC=C3Cl)C [1] |
| InChI | InChI=1S/C16H15ClN2OS/c1-3-10-8-12-15(11-6-4-5-7-13(11)17)18-9-14(20)19(2)16(12)21-10/h4-8H,3,9H2,1-2H3 [1] |
| InChIKey | CHBRHODLKOZEPZ-UHFFFAOYSA-N [1] |
| Dosing [] | |
|---|---|
| Elimination half-life | 4 hours[4] |
Clotiazepam
Clotiazepam (also known as Trecalmo, Rizen, Tienor, Clotiazepamum, Distensan, Clozan, Y 6047, 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno(2,3-e)-1,4-diazepin-2-one, 5-(2-Chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2H-thieno(2,3-e)(1,4)diazepin-2-one or Y-6047) is a
Chemistry
Stereochemistry []
Clotiazepam is a achiral mixture
Legal status
- Brazil: Clotiazepam is a B1 substance.[3]
- Canada: Clotiazepam is a Schedule IV substance.
- Germany: Clotiazepam is a prescription only/Anlage III substance.
- United Kingdom: Clotiazepam is a Class C substance.
- United States: Clotiazepam is a Schedule I under the "Controlled Substances Act (CSA)".
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 2811, Clotiazepam. Accessed June 26, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/2811
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Clotiazepam. UNII: ZCN055599V. Global Substance Registration System. Accessed June 26, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/ZCN055599V
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed June 26, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992
Clotiazépam. Economique et de Santé Publique. May 20, 2015. Accessed June 26, 2025. https://www.has-sante.fr/upload/docs/evamed/CT-14195_VERATRAN_PIC_REEVAL_RI_Avis2_CT14195.pdf