Cabergoline
Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formula	C26H37N5O2[1]
Molecular mass	451.6 g/mol[1]
Predicted LogP	3.4[1]
Melting point	102-104 °C[1]
Solubility	Insoluble[1]
Chirality	absolute[2]

Identifiers []
IUPAC name	(6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide[1]
SMILES	CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)CC=C[1]
InChI	InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1[1]
InChIKey	KORNTPPJEAJQIU-KJXAQDMKSA-N[1]

Dosing
Elimination half-life	63–69 hours (estimated)

Cabergoline

Cabergoline (also known as Cabergolina, Cabergolinum, Velactis, Caberlin, 1-((6-Allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea, 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea, 1-[(6-allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea, (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide, (8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide or Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-β)-) is a substance of the lysergamide class.

Chemistry

Stereochemistry

Cabergoline is a absolute mixture

Legal status

• Australia: Cabergoline is a S4.^[3]
• United States: Cabergoline is a prescription only.

See also

• Substituted lysergamides
• Anodyne

External links

• Cabergoline (Wikipedia)
• Cabergoline (Wikidata)
• Cabergoline (DrugBank)
• Cabergoline (PubChem)
• Cabergoline (ChEMBL)
• Cabergoline (ChEBI)
• Cabergoline (Common Chemistry)
• Cabergoline (HMDB)
• Cabergoline (KEGG)
• Cabergoline (UNII)
• Cabergoline (EPA DSSTox)

References