Anodyne

Amlodipine
Amlodipine
Esters
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Amlodipine benzoate
Amlodipine benzoate
Molecular structure via molpic based on CDK
Physical properties
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408.9 g/mol [1]
Melting point199-201 [1]
DecompositionHazardous decomposition products formed under fire conditions - Carbon oxides, nitrogen oxides (NOx), sulfur oxides, hydrogen chloride gas. /Amlodipine besylate/ [1]
Solubilityslightly soluble in water [1]
[1]
Structural Identifiers
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C20H25ClN2O5 [1]
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate [1]
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN [1]
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3 [1]
InChIKeyHTIQEAQVCYTUBX-UHFFFAOYSA-N [1]
Dosing
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Elimination half-life30–50 hours
Duration of actionAt least 24 hours

Amlodipine

Amlodipine (also known as Amlocard, Amlodipino, Coroval, Lipinox, Amlodipinum, Amlodipine Free Base, 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, HGP0904, UK-4834011 or HGP-0904)

Chemistry

Salts and Esters []

Amlodipine is typically found in the form of its besylate, adipate, maleate, mesylate and malate salts

or its ester.

 []

(RS)-Amlodipine is a racemic mixture of the optical stereoisomers

Anodyne Usernotes
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0xea / Amlodipine[besylate] via Nothing to Note

Legal status []

  • Australia: Amlodipine is a S4 substance.
  • Canada: Amlodipine is a prescription only substance.
  • United Kingdom: Amlodipine is a prescription only substance.
  • United States: Amlodipine is a prescription only substance.
  • European Union: Amlodipine is a prescription only substance.