5-Chloro-β-keto-methiopropamine

Molecular structure via molpic based on CDK

Conformer []

Conformer structure via JSmol

Physical properties []
Molecular mass	203.69 g/mol ^[1]
Predicted LogP	2.6 ^[1]

Structural Identifiers []
Molecular formula	C₈H₁₀ClNOS ^[1]
IUPAC name	1-(5-chlorothiophen-2-yl)-2-(methylamino)propan-1-one ^[1]
SMILES	CC(C(=O)C1=CC=C(S1)Cl)NC ^[1]
InChI	InChI=1S/C8H10ClNOS/c1-5(10-2)8(11)6-3-4-7(9)12-6/h3-5,10H,1-2H3 ^[1]
InChIKey	VTSPXQPERGVFBV-UHFFFAOYSA-N ^[1]

5-Chloro-β-keto-methiopropamine

5-Chloro-β-keto-methiopropamine (also known as 1-(5-Chloro-2-thienyl)-2-(methylamino)-1-propanone or 1-Propanone, 1-(5-chloro-2-thienyl)-2-(methylamino)-) is a stimulant substance of the thiopropamine class.

Chemistry

Stereochemistry []

5-Chloro-β-keto-methiopropamine is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-5-Chloro-β-keto-methiopropamine (-)-5-Chloro-β-keto-methiopropamine

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 82282703, 5-Chloro-β-keto-methiopropamine. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/82282703
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 5-Chloro-β-keto-methiopropamine. UNII: 4F8W3K5FA4. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/4F8W3K5FA4

Anodyne