3-Chlorophenylpiperazine
| 3-CPP | |
|---|---|
 |
| Salts [] | |
|---|---|
| 3-Chlorophenylpiperazine hydrochloride | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 196.67 g/mol [1] |
| Predicted LogP | 1.7 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C10H13ClN2 [1] |
| IUPAC name | 1-(3-chlorophenyl)piperazine [1] |
| SMILES | C1CN(CCN1)C2=CC(=CC=C2)Cl [1] |
| InChI | InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 [1] |
| InChIKey | VHFVKMTVMIZMIK-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 4 – 14 hours[4][5] |
3-Chlorophenylpiperazine (also known as 1-(3-Chlorophenyl)piperazine, 6640-24-0, m-Chlorophenylpiperazine, m-CPP, 1-(m-Chlorophenyl)piperazine, 3-chlorophenylpiperazine, REY0CNO998, Dtxsid9045138, NSC-49307 or J227.960F) is a
Chemistry
Salts []
3-Chlorophenylpiperazine is typically found in the form of its hydrochloride salt.
Stereochemistry []
3-Chlorophenylpiperazine is a achiral mixture.
Pharmacology
ATC Classification
Metabolism
Subjective effects []
Legal status []
- Brazil: 3-Chlorophenylpiperazine is a F2 substance.[3]
- Germany: 3-Chlorophenylpiperazine is a Anlage II substance.
See also []
External links []
- 3-Chlorophenylpiperazine (Wikipedia)
- 3-Chlorophenylpiperazine (Wikidata)
- 3-Chlorophenylpiperazine (DrugBank)
- 3-Chlorophenylpiperazine (PubChem)
- 3-Chlorophenylpiperazine (Common Chemistry)
- 3-Chlorophenylpiperazine (HMDB)
- 3-Chlorophenylpiperazine (KEGG)
- 3-Chlorophenylpiperazine (UNII)
- 3-Chlorophenylpiperazine (EPA DSSTox)
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 1355, 1-(3-Chlorophenyl)piperazine. Accessed March 23, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/1355
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 3-Chlorophenylpiperazine. UNII: REY0CNO998. Global Substance Registration System. Accessed March 23, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/REY0CNO998
Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed March 23, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451
Rotzinger S, Bourin M, Akimoto Y, Coutts RT, Baker GB. Metabolism of some "second"- and "fourth"-generation antidepressants: iprindole, viloxazine, bupropion, mianserin, maprotiline, trazodone, nefazodone, and venlafaxine. Cellular and Molecular Neurobiology. August 1, 1999; 19(4):427–442.
Schatzberg AF,Nemeroff CB. The American Psychiatric Association Publishing Textbook of Psychopharmacology, Fifth Edition. American Psychiatric Pub. Accessed March 23, 2026. https://books.google.com/books?id=KfHEDgAAQBAJ&pg=PA460