{"Abbreviation":["3-CPP"],"Aliases":["1-(3-Chlorophenyl)piperazine","6640-24-0","m-Chlorophenylpiperazine","m-CPP","1-(m-Chlorophenyl)piperazine","3-chlorophenylpiperazine","REY0CNO998","Dtxsid9045138","NSC-49307","J227.960F","Dtxcid7025138","Chebi:10588","1-3-CPP","dihydrochloro phenyl piperazine","229-654-7","3-Chlorophenyl piperazine","1-(3-Chlorophenyl) piperazine","CHEMBL478","m-chlorophenylpiperazine","Mfcd00040732","Ncgc00015247-04","(3-chlorophenyl)piperazine","1-(3-Chlorophenyl)-piperazine","NSC 49307","4-(3-Chlorophenyl)piperazine","Cas-6640-24-0","Piperazine, (3-chlorophenyl)-","Piperazine, 1-(3-chlorophenyl)-","3CPP","Einecs 229-654-7","meta-chlorophenylpiperazine","Unii-rey0cno998","meta chlorophenyl piperazine","1-(3-chlorophenyl)-piperazine","N-(3-Chlorophenyl)piperazine","Tocris-0875","TRAZODONE_met016","Lopac-C-5554","(m-CPP)","Biomol-NT_000129","Ec 229-654-7","meta-chlorophenyl-piperazine","(3-chlorophenyl)-piperazine","Lopac0_000245","Schembl48931","4-(m-chlorophenyl)piperazine","GTPL142","(3-chloro-phenyl)-piperazine","N-(m-chlorophenyl)-piperazine","Schembl218554","4-(3-chlorophenyl)-piperazine","BPBio1_000067","Schembl4885913","Schembl5099802","Schembl8317392","Schembl29128246","Schembl29361195","1-(3-chloro-phenyl)-piperazine","Piperazine, 1-(m-chlorophenyl)-","CS-D0555","PXB92343","Tox21_110110","Bdbm50001915","Pdsp1_000002","Pdsp2_000002","SBB003579","STK397316","Akos000101295","Tox21_110110_1","1-M-Chlorophenyl Piperazine Metabolite","CCG-204340","DB12110","GF-0110","Ncgc00015247-01","Ncgc00015247-02","Ncgc00015247-03","Ncgc00015247-05","Ncgc00015247-07","Ncgc00024836-01","Ncgc00024836-02","Ncgc00024836-03","AC-23379","DB-024578","NS00000404","ST45255371","Ocp_197.0840_11.1","L000009","Q286112","Brd-k75844781-001-01-9","Brd-k75844781-003-03-1","Brd-k75844781-003-08-0"],"CAS":"6640-24-0","ChemicalClasses":["phenylpiperazine"],"Chirality":"achiral","EliminationHalfLife":"4 – 14 hours\u003ca href='#cite_note-4'\u003e\u003csup\u003e[4]\u003c/sup\u003e\u003c/a\u003e\u003ca href='#cite_note-5'\u003e\u003csup\u003e[5]\u003c/sup\u003e\u003c/a\u003e","Esters":[],"European Community (EC) Number":"229-654-7","Formating":[],"HMDB ID":"HMDB0061008","HeavyAtomCount":13,"Human Drugs":"Pharmaceuticals","IUPACName":"1-(3-chlorophenyl)piperazine","InChI":"InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2","InChIKey":"VHFVKMTVMIZMIK-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0064075","Link":"https://id.nlm.nih.gov/mesh/M0064075.html","Name":"1-(3-chlorophenyl)piperazine","Ref":67},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":69},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":84},{"Id":"M0026371","Link":"https://id.nlm.nih.gov/mesh/M0026371.html","Name":"Serotonin Receptor Agonists","Ref":85}],"MeSH Pharmacological Classification":[{"Id":"M0026371","Link":"https://id.nlm.nih.gov/mesh/M0026371.html","Name":"Serotonin Receptor Agonist","Ref":85}],"Metabolism/Metabolites":"1-(3-Chlorophenyl)piperazine has known human metabolites that include 2-chloro-4-(piperazin-1-yl)phenol.","MolecularFormula":"C\u003csub\u003e10\u003c/sub\u003eH\u003csub\u003e13\u003c/sub\u003eClN\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"196.67 g/mol","PubChemId":1355,"Record Description":["Wikipedia|List of designer drugs|Piperazines"],"Records":{"UNII":{"Impurities":[]}},"RefChem":"74314","RefCount":6,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Meta-Chlorophenylpiperazine","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q286112","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB12110","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/1355","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=6640-24-0","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0061008","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C11738","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/REY0CNO998","Name":"3-Chlorophenylpiperazine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID9045138","Name":"3-Chlorophenylpiperazine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 1355, 1-(3-Chlorophenyl)piperazine. Accessed March 23, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/1355\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/1355\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 3-Chlorophenylpiperazine. UNII: REY0CNO998. Global Substance Registration System. Accessed March 23, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/REY0CNO998\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/REY0CNO998\u003c/a\u003e","Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed March 23, 2026. \u003ca href=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003ehttps://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003c/a\u003e","Rotzinger S, Bourin M, Akimoto Y, Coutts RT, Baker GB. Metabolism of some \"second\"- and \"fourth\"-generation antidepressants: iprindole, viloxazine, bupropion, mianserin, maprotiline, trazodone, nefazodone, and venlafaxine. Cellular and Molecular Neurobiology. August 1, 1999; 19(4):427–442.","Schatzberg AF,Nemeroff CB. The American Psychiatric Association Publishing Textbook of Psychopharmacology, Fifth Edition. American Psychiatric Pub. 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