Anodyne

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DOTFM
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Conformer structure via JSmol
Physical properties
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263.26 g/mol [1]
2.8 [1]
Structural Identifiers
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C12H16F3NO2 [1]
1-[2,5-dimethoxy-4-(trifluoromethyl)phenyl]propan-2-amine [1]
CC(CC1=CC(=C(C=C1OC)C(F)(F)F)OC)N [1]
InChI=1S/C12H16F3NO2/c1-7(16)4-8-5-11(18-3)9(12(13,14)15)6-10(8)17-2/h5-7H,4,16H2,1-3H3 [1]
InChIKeyWPGOTSORDNBMHP-UHFFFAOYSA-N [1]

2,5-Dimethoxy-4-trifluoromethylamphetamine

2,5-Dimethoxy-4-trifluoromethylamphetamine (also known as Racemic DOTFM, 2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methyl-ethylamine, Q4596793, 1-[2,5-Dimethoxy-4-(trifluoromethyl)phenyl]-2-propanamine, 2,5-Dimethoxy-α-methyl-4-(trifluoromethyl)benzeneethanamine or Benzeneethanamine, 2,5-dimethoxy-α-methyl-4-(trifluoromethyl)-) is a psychedelic substance of the 2,5-dimethoxyamphetamine class.

Chemistry

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2,5-Dimethoxy-4-trifluoromethylamphetamine is a racemic mixture of the

Stereoisomers
(R)-2,5-Dimethoxy-4-trifluoromethylamphetamineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-2,5-Dimethoxy-4-trifluoromethylamphetamineGenerated by the Chemistry Development Kit (http://github.com/cdk)

See also []

  • 4-Substituted 2,5-dimethoxyamphetamines (DOx)
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 10400521, 2,5-Dimethoxy-4-trifluoromethylamphetamine. Accessed July 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/10400521

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-Dimethoxy-4-trifluoromethylamphetamine. UNII: NLH3FWZ9T4. Global Substance Registration System. Accessed July 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/NLH3FWZ9T4