Anodyne

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DON
Generated by the Chemistry Development Kit (http://github.com/cdk)
Salts
[]
Hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
240.26 g/mol [1]
1.7 [1]
Structural Identifiers
[]
C11H16N2O4 [1]
1-(2,5-dimethoxy-4-nitrophenyl)propan-2-amine [1]
CC(CC1=CC(=C(C=C1OC)[N+](=O)[O-])OC)N [1]
InChI=1S/C11H16N2O4/c1-7(12)4-8-5-11(17-3)9(13(14)15)6-10(8)16-2/h5-7H,4,12H2,1-3H3 [1]
InChIKeyJQJRESSXOVAECC-UHFFFAOYSA-N [1]

2,5-Dimethoxy-4-nitroamphetamine

2,5-Dimethoxy-4-nitroamphetamine (also known as 1-(2,5-Dimethoxy-4-nitrophenyl)-2-aminopropane, J275.080E, Benzeneethanamine, 2,5-dimethoxy-α-methyl-4-nitro-, Don, L000870, Q4596794, 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine, (-)2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine, (+/-)2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine or 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine(DON)) is a psychedelic substance of the 2,5-dimethoxyamphetamine class.

Chemistry

Salts []

2,5-Dimethoxy-4-nitroamphetamine is typically found in the form of its hydrochloride salt.

 []

2,5-Dimethoxy-4-nitroamphetamine is a racemic mixture of the

Stereoisomers
(R)-2,5-Dimethoxy-4-nitroamphetamineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-2,5-Dimethoxy-4-nitroamphetamineGenerated by the Chemistry Development Kit (http://github.com/cdk)

See also []

  • 4-Substituted 2,5-dimethoxyamphetamines (DOx)
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 105432, 2,5-Dimethoxy-4-nitroamphetamine. Accessed July 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/105432

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-Dimethoxy-4-nitroamphetamine. UNII: 3FIV60666J. Global Substance Registration System. Accessed July 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/3FIV60666J