2,5-dimethoxy-4-bromobenzylpiperazine

2C-B-BZP

Molecular structure via molpic based on CDK

Rotamer []

Conformer structure via 3Dmol.js

Physical properties []
Molecular mass	315.21 g/mol ^[1]
Predicted LogP	1.7 ^[1]

Structural Identifiers []
Molecular formula	C₁₃H₁₉BrN₂O₂ ^[1]
IUPAC name	1-[(4-bromo-2,5-dimethoxyphenyl)methyl]piperazine ^[1]
SMILES	COC1=CC(=C(C=C1CN2CCNCC2)OC)Br ^[1]
InChI	InChI=1S/C13H19BrN2O2/c1-17-12-8-11(14)13(18-2)7-10(12)9-16-5-3-15-4-6-16/h7-8,15H,3-6,9H2,1-2H3 ^[1]
InChIKey	OHXVYXBOJDDYJS-UHFFFAOYSA-N ^[1]

2,5-dimethoxy-4-bromobenzylpiperazine (also known as 1-((4-Bromo-2,5-dimethoxyphenyl)methyl)piperazine, 1094424-37-9, 2C-B-BZP, 1-[(4-Bromo-2,5-dimethoxyphenyl)methyl]piperazine, R0E29C6K2K, 4-Bromo-2,5-dimethoxy-1-benzylpiperazine, 1-(4-Bromo-2,5-dimethoxybenzyl)piperazine, Unii-r0e29c6k2k, N-(4-Bromo-2,5-dimethoxybenzyl)piperazine or 1-[(4-Bromo-2,5-dimethoxyphenyl)methyl]piperazine;) is a stimulant substance of the 1,4-dimethoxybenzene class.

Chemistry

Stereochemistry []

2,5-dimethoxy-4-bromobenzylpiperazine is a achiral mixture.

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Germany: 2,5-dimethoxy-4-bromobenzylpiperazine is a Neuer-Psychoaktiver-Stoff under the "Neue-psychoaktive-Stoffe-Gesetz (NpSG)".

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 43090477, 1-((4-Bromo-2,5-dimethoxyphenyl)methyl)piperazine. Accessed March 16, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/43090477
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-dimethoxy-4-bromobenzylpiperazine. UNII: R0E29C6K2K. Global Substance Registration System. Accessed March 16, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/R0E29C6K2K

AnodyneWiki