Anodyne

TMA-2
2,4,5-Trimethoxyamphetamine
Salts
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2,4,5-Trimethoxyamphetamine hydrochloride
2,4,5-Trimethoxyamphetamine hydrochloride
Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formulaC12H19NO3[1]
Molecular mass225.28 g/mol[1]
Predicted LogP1.7[1]
Chiralityracemic[2]
Identifiers
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IUPAC name1-(2,4,5-trimethoxyphenyl)propan-2-amine[1]
SMILESCC(CC1=CC(=C(C=C1OC)OC)OC)N[1]
InChIInChI=1S/C12H19NO3/c1-8(13)5-9-6-11(15-3)12(16-4)7-10(9)14-2/h6-8H,5,13H2,1-4H3[1]
InChIKeyTVSIMAWGATVNGK-UHFFFAOYSA-N[1]
Dosing
Duration of action8–12 hours

2,4,5-Trimethoxyamphetamine

2,4,5-Trimethoxyamphetamine (also known as TMA-2, 2,4,5-Trimethoxyamphetamin, 2,4,5-Trimethoxyphenylisopropylamine, 2,4,5-Trimethoxy-α-methylphenethylamine, Phenethylamine, 2,4,5-trimethoxy-.α.-methyl-, Phenethylamine, .α.-methyl-2,4,5-trimethoxy-, Phenethylamine, 2,4,5-trimethoxy-α-methyl-, Phenethylamine, α-methyl-2,4,5-trimethoxy-, 2,4,5-Trimethoxy-α-methylbenzeneethanamine or Benzeneethanamine, 2,4,5-trimethoxy-.α.-methyl-) is a psychedelic substance of the 2,5-dimethoxyphenethylamine class.

Chemistry

2,4,5-Trimethoxyamphetamine is typically found in the form of its hydrochloride salt.

Stereochemistry

(RS)-2,4,5-Trimethoxyamphetamine is a racemic mixture of the optical stereoisomers:

Stereoisomers
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(-)-2,4,5-Trimethoxyamphetamine

(-)-2,4,5-Trimethoxyamphetamine

See also

References

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 31014, 2,4,5-Trimethoxyamphetamine. Accessed June 17, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/31014.

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,4,5-Trimethoxyamphetamine. UNII: 713Z3SL0TJ. Global Substance Registration System. Accessed June 17, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/713Z3SL0TJ