Bupropion

Salts []
Bupropion hydrobromide
Bupropion hydrochloride
Bupropion maleate

Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formula	C13H18ClNO[1]
Molecular mass	239.74 g/mol[1]
Appearance	Pale yellow oil[1]
Predicted LogP	3.2[1]
Melting point	233-234 °C[1]
Boiling point	52 °C[1]
Solubility	Very hygroscopic and susceptible to decomposition[1]
Chirality	racemic[2]

Identifiers []
IUPAC name	2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one[1]
SMILES	CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C[1]
InChI	InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3[1]
InChIKey	SNPPWIUOZRMYNY-UHFFFAOYSA-N[1]

Dosing
Elimination half-life	Bupropion:  alpha: 0.5–1.04 beta: 11 h Hydroxybupropion: 20 h Threohydrobupropion: 37 h Erythrohydrobupropion: 33 h

Insufflated []
Threshold	1 - 26.250000000000007 mg
Light	26.250000000000007 - 75 mg
Common	75 - 150 mg
Strong	150 mg
Heavy	150 - 222.49999999999997 mg

Oral []
Threshold	1 - 82.50000000000001 tablet
Light	82.50000000000001 - 150 tablet
Common	150 - 300 tablet
Strong	300 - 450 tablet
Heavy	450 - 600 tablet

Statistically derived dosages by Sernyl

Bupropion

(Redirected from (+)-Bupropion)

Bupropion (also known as Amfebutamon, 34841-39-9, amfebutamonum, Amfebutamona, Elontril, bupropione, α-(tert-butylamino)-m-chloropropiophenone, -1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone, -2-(tert-Butylamino)-3'-chlorpropiophenon or -2-(tert-Butylamino)-3'-chloropropiophenone) is a substance of the cathinone class.

Chemistry

Bupropion is typically found in the form of its hydrobromide, hydrochloride and maleate salts.

Stereochemistry

(RS)-Bupropion is a racemic mixture of the optical stereoisomers:

Stereoisomers []
(+)-Bupropion (-)-Bupropion

Subjective effects

Legal status

• Brazil: Bupropion is a C1 substance.
• Canada: Bupropion is a prescription only substance.
• United Kingdom: Bupropion is a prescription only substance.
• United States: Bupropion is a prescription only substance.
• European Union: Bupropion is a prescription only substance.

See also

• Antidepressant
• Depressant
• Stimulant
• Cathinone
• Substituted cathinones
• Anodyne

External links

• Bupropion (Wikipedia)
• Bupropion / (+)-Bupropion / (-)-Bupropion (Wikidata)
• Bupropion (DrugBank)
• Bupropion / (+)-Bupropion / (-)-Bupropion (PubChem)
• Bupropion / (+)-Bupropion / (-)-Bupropion (ChEMBL)
• Bupropion / (+)-Bupropion / (-)-Bupropion (ChEBI)
• Bupropion / (+)-Bupropion / (-)-Bupropion (Common Chemistry)
• Bupropion (HMDB)
• Bupropion (KEGG)
• Bupropion / (+)-Bupropion / (-)-Bupropion (UNII)
• Bupropion / (+)-Bupropion / (-)-Bupropion (EPA DSSTox)