α-PVP

Salts []
α-Pyrrolidinopentiophenone hydrochloride

Molecular structure via molpic

Conformer structure via 3Dmol.js
Molecular formula	C₁₅H₂₁NO^[1]
Molecular mass	231.33 g/mol^[1]
Predicted LogP	3.4^[1]
Chirality	racemic^[2]

Identifiers []
IUPAC name	1-phenyl-2-pyrrolidin-1-ylpentan-1-one^[1]
SMILES	CCCC(C(=O)C1=CC=CC=C1)N2CCCC2^[1]
InChI	InChI=1S/C15H21NO/c1-2-8-14(16-11-6-7-12-16)15(17)13-9-4-3-5-10-13/h3-5,9-10,14H,2,6-8,11-12H2,1H3^[1]
InChIKey	YDIIDRWHPFMLGR-UHFFFAOYSA-N^[1]

Dosing
Elimination half-life	2 hours
Duration of action	3 – 5 hours

α-Pyrrolidinopentiophenone

α-Pyrrolidinopentiophenone (also known as α-pyrrolidinovalerophenone, Desmethyl pyrovalerone, O-2387, J3.169.878b, α-PVP, Flakka, Prolintanone, β-Ketone-prolintane, β-Keto-prolintane or Gravel) is a stimulant substance of the pyrrolidinophenone class.

Chemistry

α-Pyrrolidinopentiophenone is typically found in the form of its hydrochloride salt.

Stereochemistry

α-Pyrrolidinopentiophenone is a racemic mixture of the optical stereoisomers:

Stereoisomers []
(+)-α-Pyrrolidinopentiophenone (-)-α-Pyrrolidinopentiophenone

Subjective effects

Physical effects []
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects []
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status

Australia: α-Pyrrolidinopentiophenone is a S8 substance.
Brazil: α-Pyrrolidinopentiophenone is a F2 substance.^[3]
Canada: α-Pyrrolidinopentiophenone is a Unscheduled substance.
United Kingdom: α-Pyrrolidinopentiophenone is a Class B substance.
United States: α-Pyrrolidinopentiophenone is a Schedule I under the "Controlled Substances Act (CSA)".
Germany: α-Pyrrolidinopentiophenone is a Anlage II substance.
New Zealand: α-Pyrrolidinopentiophenone is a Unscheduled substance.
United Nations: α-Pyrrolidinopentiophenone is a Schedule II drug under the "Convention on Psychotropic Substances 1971".

External links

References

National Center for Biotechnology Information. PubChem Compound Summary for CID 11148955, α-Pyrrolidinopentiophenone. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/11148955
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. α-Pyrrolidinopentiophenone. UNII: 767K3AWA4R. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/767K3AWA4R
Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed July 13, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

Anodyne