α-Ethyltryptamine (αET)

αET

Esters []
α-Ethyltryptamine acetate

Molecular structure via molpic based on CDK

Conformer []

Conformer structure via JSmol

Physical properties []
Molecular mass	188.27 g/mol ^[1]
Predicted LogP	2.5 ^[1]

Structural Identifiers []
Molecular formula	C₁₂H₁₆N₂ ^[1]
IUPAC name	1-(1H-indol-3-yl)butan-2-amine ^[1]
SMILES	CCC(CC1=CNC2=CC=CC=C21)N ^[1]
InChI	InChI=1S/C12H16N2/c1-2-10(13)7-9-8-14-12-6-4-3-5-11(9)12/h3-6,8,10,14H,2,7,13H2,1H3 ^[1]
InChIKey	ZXUMUPVQYAFTLF-UHFFFAOYSA-N ^[1]

Dosing []
Elimination half-life	~8 hours
Duration of action	6 – 8 hours (100 – 150 mg)

α-Ethyltryptamine

α-Ethyltryptamine (also known as Etryptamine, 3-(2-Aminobutyl)indole, Ethyltryptamine, 3-Indolylbutylamine, Etriptamina, Monase, Ro 3-1932, Indole, 3-(2-aminobutyl)-, -Etryptamine or Etryptaminum) is a entactogen and stimulant substance of the α-alkyltryptamine class.

Chemistry

Salts and Esters []

α-Ethyltryptamine is typically found in the form of its hydrochloride and acetate salts

or its ester.

Stereochemistry []

(RS)-α-Ethyltryptamine is a racemic mixture of the optical stereoisomers

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Empathy, effection, and sociability enhancement Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Brazil: α-Ethyltryptamine is a F2 substance.^[3]
Canada: α-Ethyltryptamine is a Schedule III substance.
United States: α-Ethyltryptamine is a Schedule I under the "Controlled Substances Act (CSA)".
United Kingdom: α-Ethyltryptamine is a Class A substance.
Germany: α-Ethyltryptamine is a Anlage I substance.
United Nations: α-Ethyltryptamine is a Schedule I drug under the "Convention on Psychotropic Substances 1971".

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 8367, α-Ethyltryptamine. Accessed July 3, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/8367
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. α-Ethyltryptamine. UNII: GR181O3R32. Global Substance Registration System. Accessed July 3, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/GR181O3R32
Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed July 3, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

Anodyne