Suproclone

Suproclone

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	520.0 g/mol ^[1]
Predicted LogP	2.7 ^[1]

Structural Identifiers []
Molecular formula	C₂₂H₂₂ClN₅O₄S₂ ^[1]
IUPAC name	[6-(7-chloro-1,8-naphthyridin-2-yl)-5-oxo-3,7-dihydro-2H-[1,4]dithiino[2,3-c]pyrrol-7-yl] 4-propanoylpiperazine-1-carboxylate ^[1]
SMILES	CCC(=O)N1CCN(CC1)C(=O)OC2C3=C(C(=O)N2C4=NC5=C(C=C4)C=CC(=N5)Cl)SCCS3 ^[1]
InChI	InChI=1S/C22H22ClN5O4S2/c1-2-16(29)26-7-9-27(10-8-26)22(31)32-21-18-17(33-11-12-34-18)20(30)28(21)15-6-4-13-3-5-14(23)24-19(13)25-15/h3-6,21H,2,7-12H2,1H3 ^[1]
InChIKey	IBAUKGNDWVSETP-UHFFFAOYSA-N ^[1]

Suproclone (also known as Suproclona, 77590-92-2, 37 162 R.p., 37-162-RP, 37 162 R.P, Suproclonum, Einecs 278-486-0, RP 37162, Schembl113028 or orb2815099) is a substance of the cyclopyrrolone class.

Chemistry

Stereochemistry []

Suproclone is a racemic mixture of the enantiomers.

Stereoisomerism
(R)-Suproclone (S)-Suproclone
Stereoisomer enumberation with rdkit

Druglikeness

Lipinski's rule of five

Suproclone matches Lipinski's rule of five (violations: 1).

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 53696, Suproclone. Accessed June 12, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/53696
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Suproclone. UNII: J4AM5D708G. Global Substance Registration System. Accessed June 12, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/J4AM5D708G

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