Piperazine
| Piperazine | |
|---|---|
 |
| Salts [] | |
|---|---|
| Piperazine hydrobromide | |
| Piperazine sulfate | |
| Piperazine phosphate | |
| Piperazine tartrate | |
| Piperazine camsilate | |
| Piperazine adipate | |
| Dipiperazine tricitrate | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 86.14 g/mol [1] |
| Density | 1.1 at 68 °F (NTP, 1992) - Denser than water; will sink g/cm3 [1] |
| Appearance | Plates or leaflets from ethanol [1] |
| Odor | Typical amine odor [1] |
| Taste | Salty taste [1] |
| Melting point | 223 ° [1] |
| Boiling point | 295 ° [1] |
| Decomposition | When heated to decomposition it emits highly toxic fumes of /nitrogen oxide/. [1] |
| Solubility | Very soluble (NTP, 1992) [1] |
| Predicted LogP | -1.5 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C4H10N2 [1] |
| IUPAC name | piperazine [1] |
| SMILES | C1CNCCN1 [1] |
| InChI | InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2 [1] |
| InChIKey | GLUUGHFHXGJENI-UHFFFAOYSA-N [1] |
Piperazine (also known as Piperazine, 110-85-0, Diethylenediamine, 1,4-Diazacyclohexane, Hexahydropyrazine, Piperazidine, Piperazin, Antiren, Diethyleneimine or Dispermine) is a
Chemistry
Salts []
Piperazine is typically found in the form of its hydrobromide, sulfate, phosphate, tartrate, camsilate, adipate and tricitrate salts.
Stereochemistry []
Piperazine is a achiral mixture.
Pharmacology
ATC Classification
In the antiparasitic products, insecticides and repellents (P) piperazine actsMetabolism
Subjective effects []
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 4837, Piperazine. Accessed March 26, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/4837
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Piperazine. UNII: 1RTM4PAL0V. Global Substance Registration System. Accessed March 26, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/1RTM4PAL0V