Anodyne

Norfluoxetine
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic
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Physical properties
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Molecular mass295.30 g/mol [1]
Predicted LogP3.5 [1]
Structural Identifiers
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Molecular formulaC16H16F3NO [1]
IUPAC name3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine [1]
SMILESC1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F [1]
InChIInChI=1S/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2 [1]
InChIKeyWIQRCHMSJFFONW-UHFFFAOYSA-N [1]
Dosing

Norfluoxetine

Norfluoxetine (also known as Desmethylfluoxetine, 3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine, Norfluoxetin, 56161-73-0, 3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine, C16H16F3NO, (Phenyl-d5), Benzenepropanamine, γ-(4-(trifluoromethyl)phenoxy)-, benzenepropanamine, γ-[4-(trifluoromethyl)phenoxy]- or Norfluoxetine-d5) is a serotonin reuptake inhibitor substance of the phenylpropylamine class.

Chemistry

Stereochemistry []

Norfluoxetine is a racemic mixture of the :

Stereoisomers
SeproxetineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(R)-NorfluoxetineGenerated by the Chemistry Development Kit (http://github.com/cdk)

See also []

  • Substituted phenylpropylamines
  • Anodyne
  • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 4541, Norfluoxetine. Accessed July 21, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/4541