Anodyne

MDMC
Methylone
Molecular structure via molpic based on CDK
Physical properties
[]
207.23 g/mol [1]
0.6 [1]
Structural Identifiers
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C11H13NO3 [1]
1-(1,3-benzodioxol-5-yl)-2-(methylamino)propan-1-one [1]
CC(C(=O)C1=CC2=C(C=C1)OCO2)NC [1]
InChI=1S/C11H13NO3/c1-7(12-2)11(13)8-3-4-9-10(5-8)15-6-14-9/h3-5,7,12H,6H2,1-2H3 [1]
InChIKeyVKEQBMCRQDSRET-UHFFFAOYSA-N [1]
Dosing
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Elimination half-life5.8 – 6.9 hours[4]
Duration of action2.5 – 3.0 hours

Methylone

Methylone (also known as 2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one, BK-MDMA, βK-MDMA, 3,4-Methylenedioxy-N-methylcathinone, Methylenedioxymethcathinone, β-keto-3,4-methylenedioxymethamphetamine, J899.632F, 3,4-methylenedioxy-N-methylcathinonmethylone, 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)- or 2-(Methylamino)-1-(1,3-benzodioxol-5-yl)-1-propanone) is a substance of the cathinone and methylenedioxyphenethylamine class.

Chemistry

Salts []

Methylone is typically found in the form of its hydrochloride salt.

 []

(RS)-Methylone is a racemic mixture of the optical stereoisomers

Experience reports []

Legal status []

  • Australia: Methylone is a Unscheduled substance.
  • Brazil: Methylone is a F2 substance.[3]
  • Canada: Methylone is a Schedule I substance.
  • United Kingdom: Methylone is a Class B substance.
  • United States: Methylone is a Schedule I under the "Controlled Substances Act (CSA)".
  • Germany: Methylone is a Anlage II substance.
  • United Nations: Methylone is a Schedule II [https://www.unodc.org/LSS/Substance/Details/40f647f3-b96c-4a7a-8139-88c0ff651983] substance.

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 45789647, Methylone. Accessed June 26, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/45789647

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Methylone. UNII: L4I4B1R01F. Global Substance Registration System. Accessed June 26, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/L4I4B1R01F

  3. Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed June 26, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

  4. Poyatos L, Lo Faro AF, Berardinelli D, Sprega G, Malaca S, Pichini S, Huestis MA, Papaseit E, Pérez-Mañá C, Busardò FP, Farré M. Methylone and MDMA Pharmacokinetics Following Controlled Administration in Humans. International Journal of Molecular Sciences. November 1, 2022; 23(23)