Flurbiprofen
| Flurbiprofen | |
|---|---|
 |
| Salts [] | |
|---|---|
| Sodium Flurbiprofen | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 244.26 g/mol [1] |
| Melting point | 110-111 °C [1] |
| Solubility | 2.49e-02 g/L [1] |
| Predicted LogP | 4.2 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C15H13FO2 [1] |
| IUPAC name | 2-(3-fluoro-4-phenylphenyl)propanoic acid [1] |
| SMILES | CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O [1] |
| InChI | InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18) [1] |
| InChIKey | SYTBZMRGLBWNTM-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 4.7 – 5.7 hours |
Flurbiprofen (also known as Ansaid, Froben, Antadys, 2-(2-fluorobiphenyl-4-yl)propanoic acid, Cebutid, Zepolas, Flubiprofen, Flurbiprofene, Flurbiprofeno or 3-Fluoro-4-phenylhydratropic acid) is a nonsteroidal anti-inflammatory drug substance of the alcohol class.
Chemistry
Salts []
Flurbiprofen is typically found in the form of its sodium salt.
Stereochemistry []
Flurbiprofen is a racemic mixture of the enantiomers.
| Stereoisomerism |
|---|
| Stereoisomer enumberation with rdkit |
Pharmacology
ATC Classification
In the musculo (M) flurbiprofen acts In the musculo (M) flurbiprofen acts In the respiratory system (R) flurbiprofen acts In the sensory organs (S) flurbiprofen actsSubjective effects []
| Pilz / Flurbiprofen [] | |
|---|---|
Routes:
| |
Legal status []
- Australia: Flurbiprofen is a S2 substance.
- Canada: Flurbiprofen is a prescription only substance.
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3394, Flurbiprofen. Accessed October 15, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3394
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Flurbiprofen. UNII: 5GRO578KLP. Global Substance Registration System. Accessed October 15, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/5GRO578KLP