Clobenzorex

Salts []
Clobenzorex hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	259.77 g/mol ^[1]
Predicted LogP	4.3 ^[1]

Structural Identifiers []
Molecular formula	C₁₆H₁₈ClN ^[1]
IUPAC name	(2S)-N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine ^[1]
SMILES	C[C@@H](CC1=CC=CC=C1)NCC2=CC=CC=C2Cl ^[1]
InChI	InChI=1S/C16H18ClN/c1-13(11-14-7-3-2-4-8-14)18-12-15-9-5-6-10-16(15)17/h2-10,13,18H,11-12H2,1H3/t13-/m0/s1 ^[1]
InChIKey	LRXXRIXDSAEIOR-ZDUSSCGKSA-N ^[1]

Toxicity []
TD_Lo	Human - male: - oral: 8571 μg/kg

Clobenzorex

Clobenzorex (also known as Clobenzorexum, SD 271-12, SD-27112, SD-271-12, RefChem:577722, A08AA08, N-(o-chlorobenzyl)-α-methylphenethylamine, ((2-chlorophenyl)methyl)((2S)-1-phenylpropan-2-yl)amine, 236-434-4 or N-(o-Chlorobenzyl)-α-methylphenethylamine) is a prodrug and stimulant substance of the amphetamine class.

Chemistry

Salts []

Clobenzorex is typically found in the form of its hydrochloride salt.

Stereochemistry []

Clobenzorex is a absolute mixture

Pharmacology

Clobenzorex acts as a prodrug for:

Active metabolites []
Dextroamphetamine

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Brazil: Clobenzorex is a F2 substance.^[3]
Canada: Clobenzorex is a Schedule I substance.
United States: Clobenzorex is a Unscheduled substance.
United Kingdom: Clobenzorex is a Class B substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 735998, Clobenzorex. Accessed September 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/735998
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Clobenzorex. UNII: 4A5352XI2A. Global Substance Registration System. Accessed September 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/4A5352XI2A
Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed September 14, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

Anodyne