| AST, APD-421, APD421, APD-403, APD403, DAN-2163, DAN2163 | |
|---|---|
| Salts [] | |
|---|---|
| Amisulpride hydrochloride | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 369.5 g/mol [1] |
| Melting point | 126-127 [1] |
| Solubility | Insoluble [1] |
| Predicted LogP | 1.5 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C17H27N3O4S [1] |
| IUPAC name | 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide [1] |
| SMILES | CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC [1] |
| InChI | InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) [1] |
| InChIKey | NTJOBXMMWNYJFB-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 12 hours |
| Toxicity [] | |
|---|---|
| LD50 | Mouse: - oral: 1024 mg/kg - intraperitoneal: 175 mg/kg - subcutaneous: 224 mg/kg - intravenous: 56 mg/kg |
Amisulpride
Amisulpride (also known as Solian, Aminosultopride, Deniban, Amisulprida, Amisulpridum, Socian, Barhemsys, Sulamid, APD421 or DAN-2163) is a
Chemistry
Salts []
Amisulpride is typically found in the form of its hydrochloride salt.
Stereochemistry []
Amisulpride is a racemic mixture of the enantiomers
| Stereoisomers |
|---|
| Anodyne Usernotes [] | |
|---|---|
| 0xea / Amisulpride via Oral at 50-300mg oral |
|
Legal status
- Australia: Amisulpride is a S4 substance.
- Brazil: Amisulpride is a C1 substance.[3]
- United Kingdom: Amisulpride is a prescription only substance.
- United States: Amisulpride is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 2159, Amisulpride. Accessed September 24, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/2159
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Amisulpride. UNII: 8110R61I4U. Global Substance Registration System. Accessed September 24, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8110R61I4U
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed September 24, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992
Anodyne