Phenaridine

Phenaridine

Molecular structure via molpic based on CDK

Rotamer []

Conformer structure via 3Dmol.js

Physical properties []
Molecular mass	364.5 g/mol ^[1]
Predicted LogP	5.2 ^[1]

Structural Identifiers []
Molecular formula	C₂₄H₃₂N₂O ^[1]
IUPAC name	N-[2,5-dimethyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide ^[1]
SMILES	CCC(=O)N(C1CC(N(CC1C)CCC2=CC=CC=C2)C)C3=CC=CC=C3 ^[1]
InChI	InChI=1S/C24H32N2O/c1-4-24(27)26(22-13-9-6-10-14-22)23-17-20(3)25(18-19(23)2)16-15-21-11-7-5-8-12-21/h5-14,19-20,23H,4,15-18H2,1-3H3 ^[1]
InChIKey	ODPKHHGQKIYCTJ-UHFFFAOYSA-N ^[1]

Phenaridine (also known as N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylpropanamide, Fenaridine, 2,5-Dimethylfentanyl, S07S9928YH, Propanamide, N-(2,5-dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenyl-, N-(2,5-dimethyl-1-(2-phenylethyl)piperidin-4-yl)-n-phenylpropanamide, Dtxcid501390041, phenaridine, (2α, 4β, 5β)-, phenaridine, (2α, 4α, 5β)- or phenaridine, (2α, 4α, 5α)-) is a opioid substance of the phenethylpiperidine class.

Stereochemistry []

Phenaridine is a mixture.

Subjective effects []

class / Opioid

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

Legal status []

United States: Phenaridine is a List of Schedule I drugs (US)|Schedule I substance.^[2]

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 162056, Phenaridine. Accessed May 25, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/162056
Drug Enforcement Administration. Schedules of Controlled Substances:Temporary Placement of Fentanyl-Related Substances in Schedule I. Temporary amendment; temporary scheduling order. Federal Register. February 1, 2018; 83(25):5188–92.

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