Anodyne

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N-Methylbupropion
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Physical properties
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253.77 g/mol [1]
3.7 [1]
Structural Identifiers
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C14H20ClNO [1]
2-[tert-butyl(methyl)amino]-1-(3-chlorophenyl)propan-1-one [1]
CC(C(=O)C1=CC(=CC=C1)Cl)N(C)C(C)(C)C [1]
InChI=1S/C14H20ClNO/c1-10(16(5)14(2,3)4)13(17)11-7-6-8-12(15)9-11/h6-10H,1-5H3 [1]
InChIKeyBJLKZFUZNNATGZ-UHFFFAOYSA-N [1]

N-Methylbupropion

N-Methylbupropion (also known as N-Methylbupropion, N-methyl-bupropion, 2-(tert-butyl(methyl)amino)-1-(3-chlorophenyl)propan-1-one or 2-(N-Methyl-N-tert-butylamino)-3''-chloropropiophenone) is a stimulant substance of the amphetamine class.

Chemistry

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N-Methylbupropion is a racemic mixture of the

Stereoisomers
(R)-N-MethylbupropionGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-N-MethylbupropionGenerated by the Chemistry Development Kit (http://github.com/cdk)

Pharmacology

N-Methylbupropion acts as a for:

Active metabolites
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Bupropion Generated by the Chemistry Development Kit (http://github.com/cdk)
Hydroxybupropion Generated by the Chemistry Development Kit (http://github.com/cdk)
Threohydrobupropion Generated by the Chemistry Development Kit (http://github.com/cdk)
Erythrohydrobupropion Generated by the Chemistry Development Kit (http://github.com/cdk)

Subjective effects []

See also []

  • Substituted amphetamines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 20695745, N-Methylbupropion. Accessed August 31, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/20695745