Methiopropamine

Methiopropamine

Salts []
Methiopropamine hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	155.26 g/mol ^[1]
Predicted LogP	1.9 ^[1]

Structural Identifiers []
Molecular formula	C₈H₁₃NS ^[1]
IUPAC name	N-methyl-1-thiophen-2-ylpropan-2-amine ^[1]
SMILES	CC(CC1=CC=CS1)NC ^[1]
InChI	InChI=1S/C8H13NS/c1-7(9-2)6-8-4-3-5-10-8/h3-5,7,9H,6H2,1-2H3 ^[1]
InChIKey	HPHUWHKFQXTZPS-UHFFFAOYSA-N ^[1]

Methiopropamine (also known as 1-(Thiophen-2-yl)-2-methylaminopropane, 2-Thiopheneethylamine, N,α-dimethyl-, Dea no. 1478, Dtxsid701016914, Synthacaine component methiopropamine, Dtxcid20964655, Unii-64on2eth7i, 2-Methiopropamine, N -Methyl-1-(thiophen-2-yl)propan-2-amine or Schembl30108403) is a stimulant substance of the thiopropamine class.

Chemistry

Salts []

Methiopropamine is typically found in the form of its hydrochloride salt.

Stereochemistry []

Methiopropamine is a racemic mixture of the enantiomers.

Stereoisomerism
(R)-Methiopropamine (S)-Methiopropamine
Stereoisomer enumberation with rdkit

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Experience reports []

There are currently 25+ experience reports involving methiopropamine on Erowid:

Legal status []

Brazil: Methiopropamine is a F2 substance.^[3]
Germany: Methiopropamine is a Anlage I substance.
United Kingdom: Methiopropamine is a Class B substance.
United States: Methiopropamine is a Schedule I under the "Controlled Substances Act (CSA)".

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 436156, Methiopropamine. Accessed May 6, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/436156
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Methiopropamine. UNII: 64ON2ETH7I. Global Substance Registration System. Accessed May 6, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/64ON2ETH7I
Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed May 6, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

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